2lnl: Difference between revisions
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==Structure of human CXCR1 in phospholipid bilayers== | ==Structure of human CXCR1 in phospholipid bilayers== | ||
<StructureSection load='2lnl' size='340' side='right' caption='[[2lnl | <StructureSection load='2lnl' size='340' side='right'caption='[[2lnl]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lnl]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2lnl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LNL FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR, 10 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lnl OCA], [https://pdbe.org/2lnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lnl RCSB], [https://www.ebi.ac.uk/pdbsum/2lnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lnl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CXCR1_HUMAN CXCR1_HUMAN] Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2lnl" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[CXC chemokine receptor|CXC chemokine receptor]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Casagrande | [[Category: Casagrande F]] | ||
[[Category: Chu | [[Category: Chu M]] | ||
[[Category: Das | [[Category: Das BB]] | ||
[[Category: Kiefer | [[Category: De Angelis A]] | ||
[[Category: Maier | [[Category: Kiefer H]] | ||
[[Category: Marassi | [[Category: Maier K]] | ||
[[Category: Nothnagel | [[Category: Marassi FM]] | ||
[[Category: Opella | [[Category: Nothnagel H]] | ||
[[Category: Park | [[Category: Opella SJ]] | ||
[[Category: Park S]] | |||