3v9r: Difference between revisions
No edit summary |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of Saccharomyces cerevisiae MHF complex== | ==Crystal structure of Saccharomyces cerevisiae MHF complex== | ||
<StructureSection load='3v9r' size='340' side='right' caption='[[3v9r]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='3v9r' size='340' side='right'caption='[[3v9r]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3v9r]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3v9r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V9R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V9R FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v9r OCA], [https://pdbe.org/3v9r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v9r RCSB], [https://www.ebi.ac.uk/pdbsum/3v9r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v9r ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CENPS_YEAST CENPS_YEAST] dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (PubMed:20347428). FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:22561346).[UniProtKB:O74896]<ref>PMID:20347428</ref> <ref>PMID:22561346</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3v9r" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Large Structures]] | ||
[[Category: Ding | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Li | [[Category: Ding J]] | ||
[[Category: Yang | [[Category: Li H]] | ||
[[Category: Zhang | [[Category: Yang H]] | ||
[[Category: Zhong | [[Category: Zhang T]] | ||
[[Category: Zhou | [[Category: Zhong C]] | ||
[[Category: Zhou J]] | |||