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==Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor==
==Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor==
<StructureSection load='3uns' size='340' side='right' caption='[[3uns]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3uns' size='340' side='right'caption='[[3uns]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3uns]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UNS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3uns]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UNS FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANH:METHYL+N-[(4-METHYLPHENYL)SULFONYL]GLYCYL-3-[AMINO(IMINO)METHYL]-D-PHENYLALANINATE'>ANH</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1v2k|1v2k]], [[3unq|3unq]], [[3unp|3unp]], [[3upe|3upe]], [[3uqo|3uqo]], [[3uqv|3uqv]], [[3uqz|3uqz]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANH:METHYL+N-[(4-METHYLPHENYL)SULFONYL]GLYCYL-3-[AMINO(IMINO)METHYL]-D-PHENYLALANINATE'>ANH</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uns OCA], [https://pdbe.org/3uns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uns RCSB], [https://www.ebi.ac.uk/pdbsum/3uns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uns ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uns OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uns RCSB], [http://www.ebi.ac.uk/pdbsum/3uns PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3uns" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Trypsin|Trypsin]]
*[[Trypsin 3D structures|Trypsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bovin]]
[[Category: Bos taurus]]
[[Category: Trypsin]]
[[Category: Large Structures]]
[[Category: Kolenko, P.]]
[[Category: Kolenko P]]
[[Category: Neumann, P.]]
[[Category: Neumann P]]
[[Category: Stubbs, M T.]]
[[Category: Stubbs MT]]
[[Category: Tziridis, A.]]
[[Category: Tziridis A]]
[[Category: Duodenum]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protein binding]]
[[Category: Trypsin-like serine protease]]

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