4a53: Difference between revisions
No edit summary |
No edit summary |
||
(4 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
==Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6== | ==Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6== | ||
<StructureSection load='4a53' size='340' side='right' caption='[[4a53 | <StructureSection load='4a53' size='340' side='right'caption='[[4a53]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4a53]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4a53]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A53 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a53 OCA], [https://pdbe.org/4a53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a53 RCSB], [https://www.ebi.ac.uk/pdbsum/4a53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a53 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/EDC3_SCHPO EDC3_SCHPO] Stimulates decapping of both stable and unstable mRNA during mRNA decay. Stimulates decapping presumably by preventing the DCP1-DCP2 decapping complex from adopting an inactive conformation.<ref>PMID:22085934</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Line 14: | Line 17: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4a53" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: Braun | [[Category: Braun JE]] | ||
[[Category: Fromm | [[Category: Fromm SA]] | ||
[[Category: Hoffmann | [[Category: Hoffmann NA]] | ||
[[Category: Izaurralde | [[Category: Izaurralde E]] | ||
[[Category: Kamenz | [[Category: Kamenz J]] | ||
[[Category: Sprangers | [[Category: Sprangers R]] | ||
[[Category: Truffault | [[Category: Truffault V]] | ||