3ubb: Difference between revisions
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==The crystal structure of GlpG in complex with a phosphonofluoridate inhibitor== | ==The crystal structure of GlpG in complex with a phosphonofluoridate inhibitor== | ||
<StructureSection load='3ubb' size='340' side='right' caption='[[3ubb]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='3ubb' size='340' side='right'caption='[[3ubb]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ubb]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3ubb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UBB FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.601Å</td></tr> | ||
<tr><td class="sblockLbl"><b>[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3UB:PROPAN-2-YL+HYDROGEN+(S)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}ETHYL]PHOSPHONATE'>3UB</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ubb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ubb OCA], [https://pdbe.org/3ubb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ubb RCSB], [https://www.ebi.ac.uk/pdbsum/3ubb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ubb ProSAT]</span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </table> | ||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.,Xue Y, Chowdhury S, Liu X, Akiyama Y, Ellman J, Ha Y Biochemistry. 2012 May 8;51(18):3723-31. Epub 2012 Apr 24. PMID:22515733<ref>PMID:22515733</ref> | Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.,Xue Y, Chowdhury S, Liu X, Akiyama Y, Ellman J, Ha Y Biochemistry. 2012 May 8;51(18):3723-31. Epub 2012 Apr 24. PMID:22515733<ref>PMID:22515733</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3ubb" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli K-12]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Ha | [[Category: Ha Y]] | ||
[[Category: Xue | [[Category: Xue Y]] | ||