3spe: Difference between revisions
New page: '''Unreleased structure''' The entry 3spe is ON HOLD Authors: Aksyuk, A.A., Kurochkina, L.P., Fokine, A., Mesyanzhinov, V.V., Rossmann, M.G. Description: Crystal Structure of the Tail ... |
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The | ==Crystal structure of the tail sheath protein protease resistant fragment from bacteriophage phiKZ== | ||
<StructureSection load='3spe' size='340' side='right'caption='[[3spe]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3spe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phiKZ Pseudomonas virus phiKZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3996Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spe OCA], [https://pdbe.org/3spe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spe RCSB], [https://www.ebi.ac.uk/pdbsum/3spe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8SDD3_BPDPK Q8SDD3_BPDPK] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Bacteriophage phiKZ is a giant phage that infects Pseudomonas aeruginosa, a human pathogen. The phiKZ virion consists of a 1450 A diameter icosahedral head and a 2000 A-long contractile tail. The structure of the whole virus was previously reported, showing that its tail organization in the extended state is similar to the well-studied Myovirus bacteriophage T4 tail. The crystal structure of a tail sheath protein fragment of phiKZ was determined to 2.4 A resolution. Furthermore, crystal structures of two prophage tail sheath proteins were determined to 1.9 and 3.3 A resolution. Despite low sequence identity between these proteins, all of these structures have a similar fold. The crystal structure of the phiKZ tail sheath protein has been fitted into cryo-electron-microscopy reconstructions of the extended tail sheath and of a polysheath. The structural rearrangement of the phiKZ tail sheath contraction was found to be similar to that of phage T4. | |||
Structural conservation of the myoviridae phage tail sheath protein fold.,Aksyuk AA, Kurochkina LP, Fokine A, Forouhar F, Mesyanzhinov VV, Tong L, Rossmann MG Structure. 2011 Dec 7;19(12):1885-94. PMID:22153511<ref>PMID:22153511</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 3spe" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas virus phiKZ]] | |||
[[Category: Aksyuk AA]] | |||
[[Category: Fokine A]] | |||
[[Category: Kurochkina LP]] | |||
[[Category: Mesyanzhinov VV]] | |||
[[Category: Rossmann MG]] | |||