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==Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4==
==Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4==
<StructureSection load='2lew' size='340' side='right' caption='[[2lew]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lew' size='340' side='right'caption='[[2lew]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lew]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEW FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEW FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ley|2ley]], [[2gw9|2gw9]], [[2gwp|2gwp]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Defa4, Defcr4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lew OCA], [https://pdbe.org/2lew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lew RCSB], [https://www.ebi.ac.uk/pdbsum/2lew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lew ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lew OCA], [http://pdbe.org/2lew PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lew RCSB], [http://www.ebi.ac.uk/pdbsum/2lew PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DEFA4_MOUSE DEFA4_MOUSE]] Probably contributes to the antimicrobial barrier function of the small bowel mucosa.  
[https://www.uniprot.org/uniprot/DEFA4_MOUSE DEFA4_MOUSE] Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Defensin|Defensin]]
*[[Defensin 3D structures|Defensin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Andersson, H S]]
[[Category: Mus musculus]]
[[Category: Bengtsson, E]]
[[Category: Andersson HS]]
[[Category: Craik, D J]]
[[Category: Bengtsson E]]
[[Category: Daly, N L]]
[[Category: Craik DJ]]
[[Category: Haugaard-Kedstrom, L M]]
[[Category: Daly NL]]
[[Category: Rosengren, K]]
[[Category: Haugaard-Kedstrom LM]]
[[Category: Antimicrobial protein]]
[[Category: Rosengren K]]

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