2ldf: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ldf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atractaspis_microlepidota_microlepidota Atractaspis microlepidota microlepidota]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LDF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ldf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atractaspis_microlepidota_microlepidota Atractaspis microlepidota microlepidota]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LDF FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ldf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ldf OCA], [https://pdbe.org/2ldf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ldf RCSB], [https://www.ebi.ac.uk/pdbsum/2ldf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ldf ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ldf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ldf OCA], [https://pdbe.org/2ldf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ldf RCSB], [https://www.ebi.ac.uk/pdbsum/2ldf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ldf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRTXL_ATRMM SRTXL_ATRMM] Vasoconstrictor activity. These toxins cause cardiac arrest probably as a result of coronary vasospasm. The major effects of sarafotoxin-m are a progressive decrease in heart rate (bradycardia) that turns into an arrhythmic phase that is followed by an A-V block.<ref>PMID:15350691</ref>  Sarafotoxin-m: vasoconstrictor activity. Causes cardiac arrest probably as a result of coronary vasospasm (By similarity). Displays low agonistic activities towards endothelin-2 receptor (EDNRB) (displays affinity in the micromolar range) (PubMed:21889567).<ref>PMID:15350691</ref> <ref>PMID:21889567</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

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OCA