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==The crystal structure of GxGD membrane protease FlaK==
==The crystal structure of GxGD membrane protease FlaK==
<StructureSection load='3s0x' size='340' side='right' caption='[[3s0x]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<StructureSection load='3s0x' size='340' side='right'caption='[[3s0x]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3s0x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. The August 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Rhomboid Protease GlpG''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_8 10.2210/rcsb_pdb/mom_2011_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S0X FirstGlance]. <br>
<table><tr><td colspan='2'>[[3s0x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. The August 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Rhomboid Protease GlpG''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_8 10.2210/rcsb_pdb/mom_2011_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S0X FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MmarC6_0338 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 Methanococcus maripaludis])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s0x RCSB], [http://www.ebi.ac.uk/pdbsum/3s0x PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0x OCA], [https://pdbe.org/3s0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s0x RCSB], [https://www.ebi.ac.uk/pdbsum/3s0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s0x ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FLAK_METM6 FLAK_METM6] Cleaves the N-terminal leader peptide from preflagellins.<ref>PMID:21765428</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The crystal structure of GXGD membrane protease FlaK.,Hu J, Xue Y, Lee S, Ha Y Nature. 2011 Jul 17;475(7357):528-31. doi: 10.1038/nature10218. PMID:21765428<ref>PMID:21765428</ref>
The crystal structure of GXGD membrane protease FlaK.,Hu J, Xue Y, Lee S, Ha Y Nature. 2011 Jul 17;475(7357):528-31. doi: 10.1038/nature10218. PMID:21765428<ref>PMID:21765428</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3s0x" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanococcus maripaludis]]
[[Category: Methanococcus maripaludis]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Rhomboid Protease GlpG]]
[[Category: Rhomboid Protease GlpG]]
[[Category: Ha, Y.]]
[[Category: Ha Y]]
[[Category: Hu, J.]]
[[Category: Hu J]]
[[Category: Xue, Y.]]
[[Category: Xue Y]]
[[Category: Aspartyl protease]]
[[Category: Gxgd protease]]
[[Category: Hydrolase]]
[[Category: Intramembrane proteolysis]]
[[Category: Membrane protein]]
[[Category: Preflagellin peptidase]]

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