Glycoproteins B and D: Difference between revisions
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<StructureSection load='2gum' size='350' side='right' caption='Herpes virus glycoprotein B trimer complex with Na+ ion (purple) (PDB entry [[2gum]])' scene=''> | |||
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'''Glycoproteins B, D''' (gB, gD) are components of the cell-entry complex of herpes viruses<ref>PMID:16840698</ref><ref>PMID:21980294</ref>. | |||
*'''Glycoprotein B''' is required after herpes simplex virus attachment but before the expression of viral proteins<ref>PMID:2839688</ref>. | |||
*'''Glycoprotein D''' determines which cells can be infected by herpes simplex virus by binding to the cell receptors which mediate the viral entry<ref>PMID:15273289</ref>. | |||
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</StructureSection> | |||
== 3D Structures of Glycoproteins B and D == | == 3D Structures of Glycoproteins B and D == | ||
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*Glycoprotein B | *Glycoprotein B | ||
**[[3nw8]], [[3nwa]], [[3nwd]], [[3nwf]], [[4hsi]], [[4l1r]] – | **[[6bm8]], [[5v2s]] – Hhv1gB – Human herpes virus 1<br /> | ||
**[[ | **[[6z9m]] – Hhv1gB – Cryo EM<br /> | ||
**[[2gum]], [[4bom]] - Hhv1gB extracellular domain<br /> | |||
**[[3nw8]], [[3nwa]], [[3nwd]], [[3nwf]], [[4hsi]], [[4l1r]] – Hhv1gB extracellular domain 30-730 (mutant) <br /> | |||
**[[7uhz]], [[7ui0]] – Hhv1gB + antibody – Human alphaherpesvirus 1 – Cryo EM<br /> | |||
**[[6vn1]] – Hhv3gB + antibody – Human alphaherpesvirus 3 – Cryo EM<br /> | |||
**[[7k1s]] – Hhv3gB – Cryo EM<br /> | |||
**[[6vlk]] – Hhv3gB <br /> | |||
**[[7kdd]] – Hhv5gB + antibody – Human herpes virus 5 - Cryo EM<br /> | |||
**[[6uoe]] – Hhv5gB + antibody<br /> | |||
**[[7kdp]] – Hhv5gB + inhibitor – Cryo EM<br /> | |||
**[[6esc]], [[5ys6]] - ShvgB – Suid alphaherpesvirus 1<br /> | |||
**[[5ys2]] - ShvgB domain IV 62-148 546-700 <br /> | |||
**[[5zs0]] - ShvgB domain IV + antibody <br /> | |||
**[[4osn]] – hCVgB – human cytomegalovirus<br /> | **[[4osn]] – hCVgB – human cytomegalovirus<br /> | ||
**[[4ot1]] – hCVgB + antibody<br /> | **[[5cxf]] – hCVgB (mutant)<br /> | ||
**[[4ot1]], [[5c6t]] – hCVgB + antibody<br /> | |||
**[[6vlk]] – gB – varicella-zoster virus<br /> | |||
**[[3fvc]] – EbvgB – Epstein-Barr virus <br /> | |||
**[[7fbi]] – EbvgB + antibody - Cryo EM<br /> | |||
*Glycoprotein D | *Glycoprotein D | ||
**[[2c3a]], [[2c36]], [[1l2g]], [[4myv]] – | **[[2c3a]], [[2c36]], [[1l2g]], [[4myv]] – Hhv1gD extracellular domain <br /> | ||
**[[1jma]] – | **[[4myv]] – Hhv2gD extracellular domain - Human herpes virus 2<br /> | ||
**[[3sku]] – | **[[5x5v]] – prv-gD – peudorabies virus<br /> | ||
**[[3u82]], [[4myw]] – | **[[5x5w]] – prv-gD + nectin-1<br /> | ||
**[[3w9e]] – | **[[1jma]] – Hhv1gD extracellular domain (mutant) + herpes virus entry mediator (mutant)<br /> | ||
**[[3sku]] – Hhv1gD extracellular domain + herpes virus entry mediator<br /> | |||
**[[3u82]], [[4myw]] – Hhv2gD extracellular domain + poliovirus receptor-related protein<br /> | |||
**[[3w9e]] – Hhv2gD + antibody<br /> | |||
**[[6ls9]] - bgD – bovine alphaherpesvirus 1<br /> | |||
**[[6lsa]] – bgD + nectin-1<br /> | |||
**[[6sqj]] - gD – equine alphaherpesvirus 1<br /> | |||
**[[6tm8]] - gD – equine alphaherpesvirus 4<br /> | |||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||