3r6b: Difference between revisions
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==Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3== | ==Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3== | ||
<StructureSection load='3r6b' size='340' side='right' caption='[[3r6b]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='3r6b' size='340' side='right'caption='[[3r6b]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3r6b]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3r6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R6B FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr><td class="sblockLbl"><b>[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r6b OCA], [https://pdbe.org/3r6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r6b RCSB], [https://www.ebi.ac.uk/pdbsum/3r6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r6b ProSAT]</span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </table> | ||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/TSP1_HUMAN TSP1_HUMAN] Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties.<ref>PMID:11134179</ref> <ref>PMID:15014436</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.,Klenotic PA, Page RC, Misra S, Silverstein RL Protein Expr Purif. 2011 Jul 29. PMID:21821127<ref>PMID:21821127</ref> | Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.,Klenotic PA, Page RC, Misra S, Silverstein RL Protein Expr Purif. 2011 Jul 29. PMID:21821127<ref>PMID:21821127</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3r6b" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Thrombospondin|Thrombospondin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Klenotic PA]] | ||
[[Category: | [[Category: Misra S]] | ||
[[Category: | [[Category: Page RC]] | ||
[[Category: | [[Category: Silverstein RL]] | ||