2yd8: Difference between revisions
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== | |||
<StructureSection load='2yd8' size='340' side='right' caption='[[2yd8]], [[Resolution|resolution]] 2.05Å' scene=''> | ==Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase LAR in complex with sucrose octasulphate== | ||
<StructureSection load='2yd8' size='340' side='right'caption='[[2yd8]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yd8]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2yd8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YD8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YYJ:[(2R,3S,4R,5R)-2-oxidanyl-3,4-disulfooxy-5-(sulfooxymethyl)oxolan-2-yl]methyl+hydrogen+sulfate'>YYJ</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yd8 OCA], [https://pdbe.org/2yd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yd8 RCSB], [https://www.ebi.ac.uk/pdbsum/2yd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yd8 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2yd8" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Aricescu | [[Category: Aricescu AR]] | ||
[[Category: Coles | [[Category: Coles CH]] | ||
[[Category: Flanagan | [[Category: Flanagan JG]] | ||
[[Category: Gallagher | [[Category: Gallagher JT]] | ||
[[Category: Jones | [[Category: Jones EY]] | ||
[[Category: Lu | [[Category: Lu W]] | ||
[[Category: Shen | [[Category: Shen Y]] | ||
[[Category: Siebold | [[Category: Siebold C]] | ||
[[Category: Sutton | [[Category: Sutton GC]] | ||
[[Category: Tenney | [[Category: Tenney AP]] | ||