3qw0: Difference between revisions

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-[[Image:3qw0.png|left|200px]]
-{{STRUCTURE_3qw0|  PDB=3qw0  |  SCENE=  }}
+==Crystal structure of the Zn-RIDC1 complex stabilized by BMB crosslinks==
+<StructureSection load='3qw0' size='340' side='right'caption='[[3qw0]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3qw0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QW0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QW0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ME9:1,1-BUTANE-1,4-DIYLBIS(1H-PYRROLE-2,5-DIONE)'>ME9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qw0 OCA], [https://pdbe.org/3qw0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qw0 RCSB], [https://www.ebi.ac.uk/pdbsum/3qw0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qw0 ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Here, we report that the approach of metal-templated ligand synthesis can be applied to construct a dimeric protein assembly ((BMOE)RIDC1(2)), which is stabilized by noncovalent interactions and flexible covalent cross-linkers around the Zn templates. Despite its flexibility, (BMOE)RIDC1(2) selectively binds Zn(II) over other divalent metals and undergoes dimerization upon metal binding. Such simultaneous fulfillment of plasticity and selectivity is a hallmark of cellular signaling events that involve ligand/metal-induced protein dimerization.
-===Crystal structure of the Zn-RIDC1 complex stabilized by BMB crosslinks===
+Templated Construction of a Zn-Selective Protein Dimerization Motif.,Salgado EN, Brodin JD, To MM, Tezcan FA Inorg Chem. 2011 Jun 7. PMID:21648390<ref>PMID:21648390</ref>
-{{ABSTRACT_PUBMED_21648390}}
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-==About this Structure==
+<div class="pdbe-citations 3qw0" style="background-color:#fffaf0;"></div>
-[[3qw0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QW0 OCA].
 ==See Also==
-*[[Cytochrome c|Cytochrome c]]
+*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:021648390</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Salgado, E N.]]
+[[Category: Large Structures]]
-[[Category: Tezcan, F A.]]
+[[Category: Salgado EN]]
-[[Category: Four-helix bundle]]
+[[Category: Tezcan FA]]
-[[Category: Oxidoreductase]]