3qkv: Difference between revisions

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 ==Crystal structure of fatty acid amide hydrolase with small molecule compound==
-<StructureSection load='3qkv' size='340' side='right' caption='[[3qkv]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
+<StructureSection load='3qkv' size='340' side='right'caption='[[3qkv]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3qkv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QKV FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3qkv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QKV FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QKV:(6-BROMO-1H,4H-SPIRO[1,3-BENZODIOXINE-2,4-PIPERIDIN]-1-YL)METHANOL'>QKV</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qj8|3qj8]], [[3qj9|3qj9]], [[3qk5|3qk5]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QKV:(6-BROMO-1H,4H-SPIRO[1,3-BENZODIOXINE-2,4-PIPERIDIN]-1-YL)METHANOL'>QKV</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Faah, Faah1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkv OCA], [https://pdbe.org/3qkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qkv RCSB], [https://www.ebi.ac.uk/pdbsum/3qkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qkv ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fatty_acid_amide_hydrolase Fatty acid amide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.99 3.5.1.99] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qkv RCSB], [http://www.ebi.ac.uk/pdbsum/3qkv PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/FAAH1_RAT FAAH1_RAT] Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 17: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 3qkv" style="background-color:#fffaf0;"></div>
 ==See Also==
@@ Line 24: / Line 26: @@
 __TOC__
 </StructureSection>
-[[Category: Fatty acid amide hydrolase]]
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Min, X]]
+[[Category: Min X]]
-[[Category: Walker, N P.C]]
+[[Category: Walker NPC]]
-[[Category: Wang, Z]]
+[[Category: Wang Z]]
-[[Category: Faah]]
-[[Category: Fatty-acid amide hydrolase]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Protein-inhibitor complex]]