3qb1: Difference between revisions
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==Interleukin-2 mutant D10== | ==Interleukin-2 mutant D10== | ||
<StructureSection load='3qb1' size='340' side='right' caption='[[3qb1]], [[Resolution|resolution]] 3.10Å' scene=''> | <StructureSection load='3qb1' size='340' side='right'caption='[[3qb1]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3qb1]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3qb1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QB1 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qb1 OCA], [https://pdbe.org/3qb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qb1 RCSB], [https://www.ebi.ac.uk/pdbsum/3qb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qb1 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN] Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN] Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3qb1" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Interleukin 3D structures|Interleukin 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Bates | [[Category: Large Structures]] | ||
[[Category: Bowman | [[Category: Bates DL]] | ||
[[Category: Boyman | [[Category: Bowman GR]] | ||
[[Category: Fathman | [[Category: Boyman O]] | ||
[[Category: Garcia | [[Category: Fathman CG]] | ||
[[Category: Khort | [[Category: Garcia KC]] | ||
[[Category: Krieg | [[Category: Khort HE]] | ||
[[Category: Levin | [[Category: Krieg C]] | ||
[[Category: Lin | [[Category: Levin AM]] | ||
[[Category: Novick | [[Category: Lin JT]] | ||
[[Category: Pande | [[Category: Novick P]] | ||
[[Category: Ring | [[Category: Pande VS]] | ||
[[Category: Su | [[Category: Ring AM]] | ||
[[Category: Su L]] | |||