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==Crystal structure of dipeptide epimerase from Cytophaga hutchinsonii complexed with Mg and dipeptide D-Ala-L-Ala==
==Crystal structure of dipeptide epimerase from Cytophaga hutchinsonii complexed with Mg and dipeptide D-Ala-L-Ala==
<StructureSection load='3q4d' size='340' side='right' caption='[[3q4d]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3q4d' size='340' side='right'caption='[[3q4d]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3q4d]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Cytophaga_hutchinsonii Cytophaga hutchinsonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q4D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q4D FirstGlance]. <br>
<table><tr><td colspan='2'>[[3q4d]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Cytophaga_hutchinsonii_ATCC_33406 Cytophaga hutchinsonii ATCC 33406]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q4D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q45|3q45]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHU2140, CHU_2140, tfdD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=985 Cytophaga hutchinsonii])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q4d OCA], [https://pdbe.org/3q4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q4d RCSB], [https://www.ebi.ac.uk/pdbsum/3q4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q4d ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chloromuconate_cycloisomerase Chloromuconate cycloisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.7 5.5.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q4d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q4d RCSB], [http://www.ebi.ac.uk/pdbsum/3q4d PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AAEP_CYTH3 AAEP_CYTH3] Catalyzes the epimerization of D-Ala-D-Ala to D-Ala-L-Ala. Has broad substrate specificity and catalyzes the epimerization of a variety of dipeptides containing an N-terminal Ala followed by a hydrophobic or polar residue, such as Val, Ser and Met (in vitro).<ref>PMID:22392983</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
<div class="pdbe-citations 3q4d" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
*[[Muconate cycloisomerase|Muconate cycloisomerase]]
*[[Muconate cycloisomerase|Muconate cycloisomerase]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chloromuconate cycloisomerase]]
[[Category: Cytophaga hutchinsonii ATCC 33406]]
[[Category: Cytophaga hutchinsonii]]
[[Category: Large Structures]]
[[Category: Gerlt, J A]]
[[Category: Gerlt JA]]
[[Category: Lukk, T]]
[[Category: Lukk T]]
[[Category: Nair, S K]]
[[Category: Nair SK]]
[[Category: Isomerase]]

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