3pmb: Difference between revisions
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==2.9 Angstrom crystal structure of bovine thrombin in tetragonal spacegroup== | ==2.9 Angstrom crystal structure of bovine thrombin in tetragonal spacegroup== | ||
<StructureSection load='3pmb' size='340' side='right' caption='[[3pmb]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='3pmb' size='340' side='right'caption='[[3pmb]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3pmb]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3pmb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMB FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pmb OCA], [https://pdbe.org/3pmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pmb RCSB], [https://www.ebi.ac.uk/pdbsum/3pmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pmb ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Thrombin|Thrombin]] | *[[Thrombin 3D Structures|Thrombin 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Desai | [[Category: Desai BJ]] | ||
[[Category: Scarsdale | [[Category: Scarsdale JN]] | ||
[[Category: Wright | [[Category: Wright HT]] | ||