3phu: Difference between revisions

<StructureSection load='3phu' size='340' side='right'caption='[[3phu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>

<table><tr><td colspan='2'>[[3phu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Crimean-Congo_hemorrhagic_fever_virus_strain_IbAr10200 Crimean-Congo hemorrhagic fever virus strain IbAr10200]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHU FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phu OCA], [https://pdbe.org/3phu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phu RCSB], [https://www.ebi.ac.uk/pdbsum/3phu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phu ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/L_CCHFI L_CCHFI] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity.

*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]

[[Category: Crimean-Congo hemorrhagic fever virus strain IbAr10200]]

[[Category: Large Structures]]

[[Category: Akutsu M]]

[[Category: Komander D]]

[[Category: Virdee S]]

[[Category: Ye Y]]