Pepsin: Difference between revisions
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==Introduction== | ==Introduction== | ||
Theodor Schwann discovered [[Pepsin]] in 1836. He named the enzyme pepsis from the Greek word peptein which means to digest. Pepsin was the first animal enzyme to be discovered, and, in 1929, it became one of the first enzymes to be crystallized, by John H. Northrop. | Theodor Schwann discovered [[Pepsin]] in 1836. He named the enzyme pepsis from the Greek word peptein which means to digest. Pepsin was the first animal enzyme to be discovered, and, in 1929, it became one of the first enzymes to be crystallized, by John H. Northrop. | ||
Pepsin was also the first crystallized protein to be studied by X-ray diffraction using the method of capillary mounting to prevent water loss <ref name="Xray">PMID: 2115088</ref>. | Pepsin was also the first crystallized protein to be studied by X-ray diffraction using the method of capillary mounting to prevent water loss <ref name="Xray">PMID: 2115088</ref>. | ||
*'''Pepsinogen''' is the inactive precursor of pepsin. It is converted to the active pepsin by the hydrochloric acid in the stomach<ref>PMID:8260073</ref>. | |||
*'''Endothiapepsin''' is pepsin from ''Endothia parasitica'' which is used for fragment screening<ref>PMID:27400756</ref>. | |||
See also: | See also: | ||
*[[Pepsin (Hebrew)]] | *[[Pepsin (Hebrew)]] | ||