3p27: Difference between revisions
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==Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota== | ==Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota== | ||
<StructureSection load='3p27' size='340' side='right' caption='[[3p27]], [[Resolution|resolution]] 2.95Å' scene=''> | <StructureSection load='3p27' size='340' side='right'caption='[[3p27]], [[Resolution|resolution]] 2.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3p27]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3p27]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P27 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p27 OCA], [https://pdbe.org/3p27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p27 RCSB], [https://www.ebi.ac.uk/pdbsum/3p27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p27 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HBS1_YEAST HBS1_YEAST] Involved in protein translation. Together with DOM34, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.<ref>PMID:16554824</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: | [[Category: Durand D]] | ||
[[Category: Gas | [[Category: Gas ME]] | ||
[[Category: Graille | [[Category: Graille M]] | ||
[[Category: Henri | [[Category: Henri J]] | ||
[[Category: Lacroute | [[Category: Lacroute F]] | ||
[[Category: Lazar | [[Category: Lazar N]] | ||
[[Category: Nicaise | [[Category: Nicaise M]] | ||
[[Category: Sraphin | [[Category: Sraphin B]] | ||
[[Category: Tilbeurgh | [[Category: Van Tilbeurgh H]] | ||
[[Category: | [[Category: Van den Elzen A]] | ||