Ferredoxin: Difference between revisions

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==Function==
==Function==


[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster.  It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced.  The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters.  '''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland.  '''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group.
[[Ferredoxin]] (Fd) is found in chloroplasts which mediates electron transfer and contains an iron-sulfur cluster.  It is involved in the photosynthesis process where its iron atoms accept or discharge electrons when they are being oxidized or reduced.  The iron-sulfur cluster can contain 2Fe-2S and is termed plant-like or 3Fe-4S or 4Fe-4S clusters.   
*'''Adrenodoxin''' (ADR) is a ferredoxin containing a 2Fe-2S group involved in electron transfer from NADPH+ to a cytochrome P-450 in the adrenal gland<ref>PMID:22556163</ref>..   
*'''Putidaredoxin''' (PUT) and '''terpredoxin''' (TER) are involved in the same reaction in bacteria and contain a 2Fe-2S group<ref>PMID:10220356</ref>.


==D14C variant of ''Pyrococcus furiosus'' ferredoxin<ref>DOI 10.1007/s00775-011-0778-7</ref>==
==D14C variant of ''Pyrococcus furiosus'' ferredoxin<ref>DOI 10.1007/s00775-011-0778-7</ref>==
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</StructureSection>
</StructureSection>


==3D structures of ferredoxin==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*2Fe-2S containing ferredoxins
**[[2kaj]], [[1dox]], [[1doy]] – SyFd +Ga – ''Synechocystis'' – NMR <br />
**[[3hui]], [[4ltu]] – Fd – ''Rhodopseudomonas palustris'' <br />
**[[1off]] – SyFd  <br />
**[[3gce]] – Fd – ''Nocardioides aromaticivorans'' <br />
**[[3lxf]] – Fd – ''Novosphingobium aromaticivorans''<br />
**[[2e4p]], [[2e4q]] - Fd – ''Pseudomonas sp.'' <br />
**[[2q3w]], [[1vm9]] - PmFd (mutant) – ''Pseudomonas mendocina'' <br />
**[[2i7f]], [[1uwm]] - RcFd  – ''Rhodobacter capsulatus'' <br />
**[[1e9m]] – RcFd - NMR<br />
**[[1rfk]], [[3p63]] - Fd – ''Cyanobacterium'' ''masticogladus laminosus'' <br />
**[[1vck]] - Fd – ''Pseudomonas resinovorans'' <br />
**[[1wri]], [[1frr]] - Fd – E''quisetum arvense'' <br />
**[[1sjg]] - PmFd– NMR <br />
**[[1iue]] - Fd– ''Plasmodium falciparum'' <br />
**[[1m2a]] – AeFd – ''Aquifex aeolicu''s <br />
**[[1m2b]], [[1m2d]], [[1f37]], [[1f5b]], [[1f5c]] – AeFd (mutant) <br />
**[[1l5p]] – Fd –  ''Trichomonas vaginali''s <br />
**[[1i7h]] - Fd  – ''Escherichia coli'' <br />
**[[1czp]], [[1qt9]], [[1frd]], [[1fxa]] - aFd– ''anabaena'' <br />
**[[1j7a]], [[1j7b]], [[1j7c]] , [[1qoa]], [[1qob]], [[1qof]], [[1qog]]- aFd  (mutant)  <br />
**[[1e0z]] – Fd – ''Halobacterium salinarium'' <br />
**[[1e10]] - Fd – ''Halobacterium halobium''<br />
**[[1pfd]] – Fd – ''Petroselinum crispum'' – NMR <br />
**[[1a70]] - Fd  (mutant) – ''Spinacia oleracea'' <br />
**[[1awd]] - Fd  – ''Chlorella fusca'' <br />
**[[2cjn]], [[2cjo]], [[1roe]] – SyFd – NMR <br />
**[[1rof]], [[5aui]], [[5auk]] – SyFd – ''Synechococcus elongates'' <br />
**[[1doi]] - Fd  – ''Haloarcula marismortui'' <br />
**[[4fxc]] – Fd – ''Spirulina platensi''s <br />
**[[1fxi]], [[3av8]] – Fd – ''Aphanothece sacrum'' <br />
**[[3dqy]], [[2qpz]], [[3ah7]] - Fd  – ''Pseudomonas putida'' <br />
**[[3ab5]], [[3wcq]] – Fd – ''Cyanidioschyzon merolae''<br />
**[[3b2f]], [[5h57]] – mFd – maize<br />
**[[3w5u]], [[3w5v]], [[1gaq]], [[5h5j]] – mFd + ferredoxin-NADP reductase<br />
**[[5h92]], [[5h8y]] – mFd + sulfite reductase<br />
**[[3b2g]] – Fd – ''Leptolyngbya boryana''<br />
**[[2mh7]] – Fd – ''Chlamydomonas reinhardtii''<br />
**[[1ewy]] – Fd + ferredoxin-NADP reductase - ''Nostoc''<br />
**[[5ffi]], [[5abr]] - AvFd – ''Azotobacter vinelandii''<br />
**[[5bok]] - Fd – ''Diaphorobacter''<br />
**[[4zhp]] - Fd – potato<br />
**[[4zho]] – AtFd-2 – ''Arabidopsis thaliana''<br />
**[[6b03]], [[6b05]], [[6brs]] – AtFd-2 + zinc protease<br />
**[[6e6s]], [[6e6r]], [[6e6q]] – PaFd (mutant)_-  ''Pseudomonas aeruginosa''<br />
*4Fe-4S containing ferredoxins
**[[3eun]] – AvFd  – ''Allochromatium vinosum'' <br />
**[[3exy]] - AvFd (mutant) <br />
**[[2vkr]] - Fd+Zn – ''Acidianus ambivalens'' <br />
**[[2z8q]] - PfFd (mutant) – ''Pyrococcus furiosus'' <br />
**[[1siz]] - PfFd<br >
**[[3pni]] - PfFd (mutant)<br />
**[[2fgo]] - PaFd <br />
**[[1iqz]], [[1ir0]] - BtFd  – ''Bacillus thermoproteolyticus'' <br />
**[[1rgv]] - Fd  – ''Thauera aromatica'' <br />
**[[1dax]], [[1dfd]] – DaFd – ''Desulfovibrio africanus'' – NMR <br />
**[[1fxr]] - DaFd  <br />
**[[1vjw]] – Fd – ''Thermotoga maritima'' <br />
**[[1dwl]] – Fd – ''Desulfomicrobium norvegicum''<br />
*3Fe-4S containing ferredoxins
**[[2v2k]] – Fd – ''Mycobacterium smegmatis'' <br />
**[[1wtf]] - BtFd (mutant)  <br />
**[[1sj1]] - PfFd  <br />
**[[1fxd]] - DgFd  – ''Desulfovibrio gigas'' <br />
**[[1f2g]] – DgFd – NMR <br />
**[[1xer]] - Fd  – ''Sulfolobus tokodaii'' <br />
*4Fe-4S+3Fe-4S containing ferredoxins
**[[1gao]], [[6fdr]], [[7fd1]], [[7fdr]], [[1axq]], [[6fd1]], [[1frh]], [[1fri]],[[1frj]], [[1frk]], [[1frl]], [[1frm]], [[1fda]], [[1fdb]], [[1fdd]], [[5fd1]], [[1fer]] – AvFd – ''Azotobacter vinelandii'' <br />
**[[1pc4]], [[1pc5]], [[1g6b]], [[1g3o]], [[1ff2]], [[1b0v]], [[1d3w]], [[1b0t]], [[1a6l]], [[1ftc]], [[1frx]], [[2fd2]], [[1fd2]] - AvFd  (mutant)  <br />
**[[1h98]] – Fd – ''Thermus thermophilus'' <br />
**[[1a8p]], [[1bd6]], [[1bc6]] - BsFd  – ''Bacillus schlegelii'' – NMR <br />
*4Fe-4S+4Fe-4S containing ferredoxins
**[[1dur]] – Fd – ''Peptoniphilus asaccarolyticus'' <br />
**[[1bwe]], [[1bqx]] - BsFd  (mutant) – NMR <br />
**[[2fdn]], [[1fca]] , [[1fdn]] - Fd – ''Clostridium acidi-urici'' <br />
**[[1blu]] - Fd – ''Chromatium vinosum'' <br />
**[[1clf]] – Fd – ''Clostridium pasteurianum'' – NMR <br />
*Adrenoredoxin
**[[2mjd]], [[2mje]] – yADR – yeast<br />
**[[2jqr]] – yADR Fd domain (mutant)+cytochrome c (mutant) – NMR <br />
**[[2bt6]] – cADR1 modified – cow <br />
**[[1l6u]], [[1l6v]] – cADR1 – NMR <br />
**[[1e6e]] – cADR (mutant)+ADR reductase <br />
**[[1cje]], [[1ayf]] - cADR <br />
**[[3na0]], [[3n9y]], [[3n9z]], [[3na1]] - hADR +cholesterol side-chain cleavage enzyme – human<br />
**[[3p1m]] - hADR<br />
**[[5uj5]] – ADR – ''Encephalitozoon cuniculi''<br />
*Putidaredoxin
**[[1yji]], [[1yjj]], [[1pdx]] – PpPUT – NMR <br />
**[[3lb8]] – PpPUT (mutant)+PUT reductase <br />
**[[1xln]], [[1xlo]], [[1xlp]], [[1xlq]], [[1r7s]], [[1oqq]], [[1oqr]] - PpPUT (mutant) <br />
**[[1gpx]], [[1put]]- PpPUT (mutant) - NMR <br />
**[[4jws]] - PpPUT + cytochrome P450cam<br />
**[[3w9c]], [[4jwu]] - PpPUT (mutant) + cytochrome P450cam<br />
**[[2m56]] - PpPUT (mutant) + cytochrome P450cam - NMR<br />
**[[4jx1]] - PpPUT (mutant) + cytochrome P450cam + camphor + hydroxycamphor<br />
*Terpredoxin
**[[1b9r]] – TER – ''Pseudomonas'' - NMR <br />
}}
==References==
==References==
<references/>
<references/>

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, David Canner, Eran Hodis, Jaime Prilusky, Alexander Berchansky, Wayne Decatur