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==Crystal structure of the alpha-galactosidase from Lactobacillus brevis, Northeast Structural Genomics Consortium Target LbR11.==
==Crystal structure of the alpha-galactosidase from Lactobacillus brevis, Northeast Structural Genomics Consortium Target LbR11.==
<StructureSection load='3mi6' size='340' side='right' caption='[[3mi6]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3mi6' size='340' side='right'caption='[[3mi6]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3mi6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_brevis Lactobacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MI6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MI6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3mi6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Levilactobacillus_brevis_ATCC_367 Levilactobacillus brevis ATCC 367]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MI6 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.704&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LVIS_1758 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1580 Lactobacillus brevis])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-galactosidase Alpha-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.22 3.2.1.22] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mi6 OCA], [https://pdbe.org/3mi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mi6 RCSB], [https://www.ebi.ac.uk/pdbsum/3mi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mi6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mi6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mi6 RCSB], [http://www.ebi.ac.uk/pdbsum/3mi6 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q03PP7_LEVBA Q03PP7_LEVBA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/3mi6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/3mi6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mi6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Galactosidase|Galactosidase]]
*[[Galactosidase 3D structures|Galactosidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alpha-galactosidase]]
[[Category: Large Structures]]
[[Category: Lactobacillus brevis]]
[[Category: Levilactobacillus brevis ATCC 367]]
[[Category: Acton, T B]]
[[Category: Acton TB]]
[[Category: Belote, R]]
[[Category: Belote R]]
[[Category: Chen, Y]]
[[Category: Chen Y]]
[[Category: Everett, J K]]
[[Category: Everett JK]]
[[Category: Hunt, J F]]
[[Category: Hunt JF]]
[[Category: Montelione, G T]]
[[Category: Montelione GT]]
[[Category: Structural genomic]]
[[Category: Sahdev S]]
[[Category: Sahdev, S]]
[[Category: Seetharaman J]]
[[Category: Seetharaman, J]]
[[Category: Tong L]]
[[Category: Tong, L]]
[[Category: Vorobiev S]]
[[Category: Vorobiev, S]]
[[Category: Xiao R]]
[[Category: Xiao, R]]
[[Category: Hydrolase]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]

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