Hemolysin: Difference between revisions

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<StructureSection load='7ahl' size='350' side='right' caption='α-hemolysin heptamer (PDB code [[7ahl]]).' scene=''>
<StructureSection load='7ahl' size='350' side='right' caption='α-hemolysin heptamer (PDB code [[7ahl]]).' scene=''>
== Function ==
== Function ==
'''Hemolysin''' (HL) is exotoxin from bacteria which causes lysis of red blood cells<ref>PMID:20110774</ref>. Hemolysin from the bacterium ''Clostridium'' are called '''alpha-toxin''' (AT).  AT is a zinc metalloenzyme and binds to the membrane in the presence of calcium. It acts as a phospholipase C.
'''Hemolysin''' (HL) is exotoxin from bacteria which causes lysis of red blood cells<ref>PMID:20110774</ref>.  
*'''alpha-hemolysin''' is a transmembrane pore-forming heptameric molecule<ref>PMID:8943190</ref>.  See details for in [[Pore forming toxin, α-hemolysin]]. 
*'''delta-hemolysin''' is a 26 amino acid peptide from the bacterium ''Staphylococcus'' exhibiting antimicrobial activity against'' Legionerlla'' <ref>PMID:19150639</ref>.  


See details for α-hemolysin in [[Pore forming toxin, α-hemolysin]]. 
See details of hemolysin E in [[Molecular Playground/ClyA]].
See details of hemolysin E in [[Molecular Playground/ClyA]].


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Wayne Decatur, Alexander Berchansky, Michal Harel, Mark Hoelzer