Hemolysin: Difference between revisions
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Hemolysin | <StructureSection load='7ahl' size='350' side='right' caption='α-hemolysin heptamer (PDB code [[7ahl]]).' scene=''> | ||
== Function == | |||
'''Hemolysin''' (HL) is exotoxin from bacteria which causes lysis of red blood cells<ref>PMID:20110774</ref>. | |||
*'''alpha-hemolysin''' is a transmembrane pore-forming heptameric molecule<ref>PMID:8943190</ref>. See details for in [[Pore forming toxin, α-hemolysin]]. | |||
*'''delta-hemolysin''' is a 26 amino acid peptide from the bacterium ''Staphylococcus'' exhibiting antimicrobial activity against'' Legionerlla'' <ref>PMID:19150639</ref>. | |||
See details of hemolysin E in [[Molecular Playground/ClyA]]. | |||
For toxins in Proteopdia see [[Toxins]]. | |||
== Relevance == | |||
HL acts as a virulence factor in the pathogenesis of invasive infections<ref>PMID:12564994</ref>. | |||
==3D Printed Physical Model of Hemolysin== | |||
Shown below is a 3D printed physical model of Hemolysin. The model is shown in alpha carbon backbone format with each chain colored uniquely. | |||
[[Image:hemolysin1_centerForBioMolecularModeling.jpg|550px]] | |||
[[Image:hemolysin2_centerForBioMolecularModeling.jpg|550px]] | |||
====The MSOE Center for BioMolecular Modeling==== | |||
[[Image:CbmUniversityLogo.jpg | left | 150px]] | |||
The [http://cbm.msoe.edu MSOE Center for BioMolecular Modeling] uses 3D printing technology to create physical models of protein and molecular structures, making the invisible molecular world more tangible and comprehensible. To view more protein structure models, visit our [http://cbm.msoe.edu/educationalmedia/modelgallery/ Model Gallery]. | |||
== 3D Structures of hemolysin == | |||
[[Hemolysin 3D structures]] | |||
</StructureSection> | |||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | |||