3ma6: Difference between revisions

New page: '''Unreleased structure''' The entry 3ma6 is ON HOLD Authors: Wernimont, A.K., Qiu, W., Amani, M, Artz, J.D., Hassani, A.A., Senisterra, G., Vedadi, M., Sibley, L.D., Lourido, S., Shoka...
 
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'''Unreleased structure'''


The entry 3ma6 is ON HOLD
==Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1==
 
<StructureSection load='3ma6' size='340' side='right'caption='[[3ma6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Wernimont, A.K., Qiu, W., Amani, M, Artz, J.D., Hassani, A.A., Senisterra, G., Vedadi, M., Sibley, L.D., Lourido, S., Shokat, K., Zhang, C., Arrowsmith, C.H.., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Hui, R., Lin, Y.H., Structural Genomics
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ma6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MA6 FirstGlance]. <br>
Description: Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXR:3-(3-BROMOBENZYL)-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>DXR</scene></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:23:45 2010''
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ma6 OCA], [https://pdbe.org/3ma6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ma6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ma6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ma6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9BJF5_TOXGO Q9BJF5_TOXGO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/3ma6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ma6 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Toxoplasma gondii]]
[[Category: Amani M]]
[[Category: Arrowsmith CH]]
[[Category: Artz JD]]
[[Category: Bochkarev A]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: Hassani AA]]
[[Category: Hui R]]
[[Category: Lin YH]]
[[Category: Lourido S]]
[[Category: Qiu W]]
[[Category: Senisterra G]]
[[Category: Shokat K]]
[[Category: Sibley LD]]
[[Category: Vedadi M]]
[[Category: Weigelt J]]
[[Category: Wernimont AK]]
[[Category: Zhang C]]

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