3m6l: Difference between revisions

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-[[Image:3m6l.png|left|200px]]
-{{STRUCTURE_3m6l|  PDB=3m6l  |  SCENE=  }}
+==Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate and calcium ion==
+<StructureSection load='3m6l' size='340' side='right'caption='[[3m6l]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
-===Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate and calcium ion===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3m6l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M6L FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=R5P:RIBOSE-5-PHOSPHATE'>R5P</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
-[[3m6l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M6L OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m6l OCA], [https://pdbe.org/3m6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m6l RCSB], [https://www.ebi.ac.uk/pdbsum/3m6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m6l ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q0P7Y3_CAMJE Q0P7Y3_CAMJE] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).[RuleBase:RU004996]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m6/3m6l_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m6l ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Transketolase|Transketolase]]
+*[[Transketolase 3D structures|Transketolase 3D structures]]
-[[Category: Campylobacter jejuni]]
+__TOC__
-[[Category: Transketolase]]
+</StructureSection>
-[[Category: Anderson, W.]]
+[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
-[[Category: Csgid]]
+[[Category: Large Structures]]
-[[Category: Joachimiak, A.]]
+[[Category: Anderson W]]
-[[Category: Makowska-Grzyska, M.]]
+[[Category: Joachimiak A]]
-[[Category: Maltseva, N.]]
+[[Category: Makowska-Grzyska M]]
-[[Category: Nocek, B.]]
+[[Category: Maltseva N]]
-[[Category: Calcium binding]]
+[[Category: Nocek B]]
-[[Category: Center for structural genomics of infectious disease]]
-[[Category: Csgid]]
-[[Category: Niaid]]
-[[Category: Ribose-5-phosphate bound]]
-[[Category: Structural genomic]]
-[[Category: Thiamine pyrophosphate]]
-[[Category: Transferase]]
-[[Category: Transketolase]]