3lu8: Difference between revisions

<table><tr><td colspan='2'>[[3lu8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LU8 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IQX:N-[5-(5-{[(2,4-DIMETHYL-1,3-THIAZOL-5-YL)SULFONYL]AMINO}-6-FLUOROPYRIDIN-3-YL)-4-METHYL-1,3-THIAZOL-2-YL]ACETAMIDE'>IQX</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lu8 OCA], [https://pdbe.org/3lu8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lu8 RCSB], [https://www.ebi.ac.uk/pdbsum/3lu8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lu8 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>  

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>  

[[Category: Buttar D]]

[[Category: Colclough N]]

[[Category: Gerhardt S]]

[[Category: MacFaul PA]]

[[Category: Maskos K]]

[[Category: Phillips SD]]

[[Category: Plowright A]]

[[Category: Steinbacher S]]

[[Category: Steuber H]]

[[Category: Tam K]]

[[Category: Whittamore P]]