3l3h: Difference between revisions

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 ==X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC==
-<StructureSection load='3l3h' size='340' side='right' caption='[[3l3h]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+<StructureSection load='3l3h' size='340' side='right'caption='[[3l3h]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3l3h]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L3H FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3l3h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/African_starling/England-Q/983/1979(H7N1)) Influenza A virus (A/African starling/England-Q/983/1979(H7N1))] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L3H FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yn6|1yn6]], [[1yn7|1yn7]], [[3l3d|3l3d]], [[3l3g|3l3g]], [[3l3i|3l3i]], [[3l3j|3l3j]], [[3l3k|3l3k]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">H2-D1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), B2m ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l3h OCA], [https://pdbe.org/3l3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l3h RCSB], [https://www.ebi.ac.uk/pdbsum/3l3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l3h ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l3h OCA], [http://pdbe.org/3l3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l3h RCSB], [http://www.ebi.ac.uk/pdbsum/3l3h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l3h ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/Q17TI0_9INFA Q17TI0_9INFA]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).[SAAS:SAAS001009_004_020464] [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
+[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 15: / Line 14: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l3/3l3h_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 31: / Line 30: @@
 ==See Also==
-*[[Beta-2 microglobulin|Beta-2 microglobulin]]
+*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-*[[Major histocompatibility complex|Major histocompatibility complex]]
+*[[MHC 3D structures|MHC 3D structures]]
+*[[MHC I 3D structures|MHC I 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Lk3 transgenic mice]]
+[[Category: Large Structures]]
-[[Category: Clements, C S]]
+[[Category: Mus musculus]]
-[[Category: Dunstone, M A]]
+[[Category: Clements CS]]
-[[Category: Rossjohn, J]]
+[[Category: Dunstone MA]]
-[[Category: Welland, A]]
+[[Category: Rossjohn J]]
-[[Category: Animals antigen]]
+[[Category: Welland A]]
-[[Category: Glycoprotein]]
-[[Category: Immune response]]
-[[Category: Immune system]]
-[[Category: Immunoglobulin domain]]
-[[Category: Membrane]]
-[[Category: Mhc i]]
-[[Category: Mice antigen]]
-[[Category: Secreted]]
-[[Category: T-cell]]
-[[Category: T-lymphocyte]]
-[[Category: T-lymphocyte histocompatibility antigen]]
-[[Category: Transmembrane]]
-[[Category: Viral epitope]]