3kv7: Difference between revisions

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 ==Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK - wild type FlK in complex with acetate==
-<StructureSection load='3kv7' size='340' side='right' caption='[[3kv7]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
+<StructureSection load='3kv7' size='340' side='right'caption='[[3kv7]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3kv7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_cattleya"_kahan_et_al._1979 "streptomyces cattleya" kahan et al. 1979]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KV7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3kv7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_cattleya Streptomyces cattleya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KV7 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kuv|3kuv]], [[3kuw|3kuw]], [[3kv8|3kv8]], [[3kvi|3kvi]], [[3kvu|3kvu]], [[3kvz|3kvz]], [[3kw1|3kw1]], [[3kx7|3kx7]], [[3kx8|3kx8]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">flK, fluoroacetyl-CoA thioesterase FlK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29303 "Streptomyces cattleya" Kahan et al. 1979])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kv7 OCA], [https://pdbe.org/3kv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kv7 RCSB], [https://www.ebi.ac.uk/pdbsum/3kv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kv7 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kv7 OCA], [http://pdbe.org/3kv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kv7 RCSB], [http://www.ebi.ac.uk/pdbsum/3kv7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kv7 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/FLK_STRCT FLK_STRCT]] Hydrolyzes fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance. Can not use acetyl-CoA as substrate.<ref>PMID:16720268</ref> <ref>PMID:20836570</ref>
+[https://www.uniprot.org/uniprot/FLK_STRCT FLK_STRCT] Hydrolyzes fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance. Can not use acetyl-CoA as substrate.<ref>PMID:16720268</ref> <ref>PMID:20836570</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/3kv7_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/3kv7_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 32: / Line 31: @@
 ==See Also==
-*[[Thioesterase|Thioesterase]]
+*[[Thioesterase 3D structures|Thioesterase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Streptomyces cattleya kahan et al. 1979]]
+[[Category: Large Structures]]
-[[Category: Blundell, T L]]
+[[Category: Streptomyces cattleya]]
-[[Category: Chirgadze, D Y]]
+[[Category: Blundell TL]]
-[[Category: Dias, M V.B]]
+[[Category: Chirgadze DY]]
-[[Category: Huang, F]]
+[[Category: Dias MVB]]
-[[Category: Leadlay, P F]]
+[[Category: Huang F]]
-[[Category: Spencer, J B]]
+[[Category: Leadlay PF]]
-[[Category: Spiteller, D]]
+[[Category: Spencer JB]]
-[[Category: Tosin, M]]
+[[Category: Spiteller D]]
-[[Category: Valentine, E F]]
+[[Category: Tosin M]]
-[[Category: Fluoroacetyl-coa thioesterase flk]]
+[[Category: Valentine EF]]
-[[Category: Hot-dog folding]]
-[[Category: Hydrolase]]
-[[Category: Thioesterase]]