3kt4: Difference between revisions

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==Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex==
==Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex==
<StructureSection load='3kt4' size='340' side='right' caption='[[3kt4]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
<StructureSection load='3kt4' size='340' side='right'caption='[[3kt4]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3kt4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KT4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3kt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KT4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.73&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kt1|3kt1]], [[3kt7|3kt7]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kt4 OCA], [https://pdbe.org/3kt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kt4 RCSB], [https://www.ebi.ac.uk/pdbsum/3kt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kt4 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPA1, YER049W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kt4 OCA], [http://pdbe.org/3kt4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kt4 RCSB], [http://www.ebi.ac.uk/pdbsum/3kt4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kt4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TPA1_YEAST TPA1_YEAST]] Part of a messenger ribonucleoprotein (mRNP) complex at the 3'-UTR of mRNAs. It associates specifically with components of the translation termination complex and is involved in both translation termination and in regulation of normal mRNA decay through translation termination-coupled poly(A) shortening.<ref>PMID:16809762</ref>
[https://www.uniprot.org/uniprot/TPA1_YEAST TPA1_YEAST] Part of a messenger ribonucleoprotein (mRNP) complex at the 3'-UTR of mRNAs. It associates specifically with components of the translation termination complex and is involved in both translation termination and in regulation of normal mRNA decay through translation termination-coupled poly(A) shortening.<ref>PMID:16809762</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kt/3kt4_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kt/3kt4_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Kim, D J]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Kim, H L]]
[[Category: Kim DJ]]
[[Category: Kim, H S]]
[[Category: Kim HL]]
[[Category: Kim, K H]]
[[Category: Kim HS]]
[[Category: Kim, S J]]
[[Category: Kim KH]]
[[Category: Lee, H Y]]
[[Category: Kim S-J]]
[[Category: Lee, J Y]]
[[Category: Lee HY]]
[[Category: Lee, S J]]
[[Category: Lee JY]]
[[Category: Park, S B]]
[[Category: Lee SJ]]
[[Category: Suh, S W]]
[[Category: Park SB]]
[[Category: Yoon, H J]]
[[Category: Suh SW]]
[[Category: Yoon, J Y]]
[[Category: Yoon HJ]]
[[Category: Dioxygenase]]
[[Category: Yoon JY]]
[[Category: Double-stranded beta helix fold]]
[[Category: Iron]]
[[Category: Mrnp complex]]
[[Category: Oxidoreductase]]
[[Category: Prolyl hydroxylase]]
[[Category: Tpa1]]

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