Ribosome: Difference between revisions
m added categories |
Michal Harel (talk | contribs) No edit summary |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 3: | Line 3: | ||
==Introduction== | ==Introduction== | ||
The [http://en.wikipedia.org/wiki/ribosome ribosome] is a complex composed of RNA and protein that adds up to several million daltons in size and plays a critical role in the process of decoding the genetic information stored in the genome into protein as outlined in what is now known as [http://sandwalk.blogspot.com/2009/10/ribosome-and-central-dogma-of-molecular.html the Central Dogma of Molecular Biology]. Specifically, the ribosome carries out the process of translation, decoding the genetic information encoded in messenger RNA, one amino acid at a time, into newly synthesized polypeptide chains. | The [http://en.wikipedia.org/wiki/ribosome ribosome] is a complex composed of RNA and protein that adds up to several million daltons in size and plays a critical role in the process of decoding the genetic information stored in the genome into protein as outlined in what is now known as [http://sandwalk.blogspot.com/2009/10/ribosome-and-central-dogma-of-molecular.html the Central Dogma of Molecular Biology]. Specifically, the ribosome carries out the process of translation, decoding the genetic information encoded in messenger RNA, one amino acid at a time, into newly synthesized polypeptide chains. | ||
*'''30S ribosome''' - prokaryote small subunit | |||
*'''40S ribosome''' - eukaryote small subunit | |||
*'''pre-40S ribosome''' - eukaryote small subunit with associated assembly factors | |||
*'''43S ribosome''' - eukaryote preinitiation small subunit containing eIF3, eIF1 and eIF1A | |||
*'''48S ribosome''' - eukaryote small subunit initiation complex containing Met-tRNA | |||
*'''50S ribosome''' - prokaryote large subunit | |||
*'''60S ribosome''' - eukaryote large subunit | |||
*'''pre-60S ribosome''' - eukaryote nucleolar large subunit with associated assembly factors | |||
*'''70S ribosome''' - prokaryote full ribosome containing small and large subunits | |||
*'''80S ribosome''' - eukaryote full ribosome containing small and large subunits | |||
*'''90S pre-ribosome''' - eukaryote an early biogenesis ribosome intermediate containing assembly factors and small nucleolar RNAs. | |||
*'''100S ribosome''' - a dimer of prokaryote full ribosomes | |||
==Nobel Prize Winners and Other Contributors== | ==Nobel Prize Winners and Other Contributors== | ||
| Line 50: | Line 63: | ||
*[[Large Ribosomal Subunit of Haloarcula]]<br /> | *[[Large Ribosomal Subunit of Haloarcula]]<br /> | ||
*[[User:Wayne_Decatur/Haloarcula Large Ribosomal Subunit With Azithromycin|Azithromycin bound to the Large Ribosomal Subunit of Haloarcula marismortui]]<br> | *[[User:Wayne_Decatur/Haloarcula Large Ribosomal Subunit With Azithromycin|Azithromycin bound to the Large Ribosomal Subunit of Haloarcula marismortui]]<br> | ||
*[[Azithromycin]]<br /> | |||
*[[Clarithromycin]]<br /> | |||
*[[Doxycycline]]<br /> | |||
*[[40S rRNA and proteins and P/E tRNA for eukaryotic ribosome]]<br /> | *[[40S rRNA and proteins and P/E tRNA for eukaryotic ribosome]]<br /> | ||
*[[Ribosomal A Site Binding Paromomycin: A Morph]]<br /> | *[[Ribosomal A Site Binding Paromomycin: A Morph]]<br /> | ||