2kmr: Difference between revisions

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OCA

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 ==Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.==
-<StructureSection load='2kmr' size='340' side='right' caption='[[2kmr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='2kmr' size='340' side='right'caption='[[2kmr]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2kmr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KMR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KMR FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2kmr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KMR FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kmo|2kmo]], [[2kmp|2kmp]], [[2kmq|2kmq]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kmr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kmr RCSB], [http://www.ebi.ac.uk/pdbsum/2kmr PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kmr OCA], [https://pdbe.org/2kmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kmr RCSB], [https://www.ebi.ac.uk/pdbsum/2kmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kmr ProSAT]</span></td></tr>
-<table>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LDTI_HIRME LDTI_HIRME] Acts as an inhibitor of human tryptase, trypsin and chymotrypsin. Probably acts to block host defense mechanisms.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/2kmr_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/2kmr_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kmr ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 24: / Line 27: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2kmr" style="background-color:#fffaf0;"></div>
 ==See Also==
@@ Line 32: / Line 36: @@
 </StructureSection>
 [[Category: Hirudo medicinalis]]
-[[Category: Pantoja-Uceda, D.]]
+[[Category: Large Structures]]
-[[Category: Santoro, J.]]
+[[Category: Pantoja-Uceda D]]
-[[Category: Disulfide bond]]
+[[Category: Santoro J]]
-[[Category: Hydrolase]]
-[[Category: Protease inhibitor]]
-[[Category: Serine protease inhibitor]]