3i6f: Difference between revisions

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[[Image:3i6f.jpg|left|200px]]


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==Ribonuclease A by Classical hanging drop method before high X-Ray dose on ESRF ID14-2 beamline==
The line below this paragraph, containing "STRUCTURE_3i6f", creates the "Structure Box" on the page.
<StructureSection load='3i6f' size='340' side='right'caption='[[3i6f]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3i6f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I6F FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_3i6f| PDB=3i6f |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i6f OCA], [https://pdbe.org/3i6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i6f RCSB], [https://www.ebi.ac.uk/pdbsum/3i6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i6f ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/3i6f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i6f ConSurf].
<div style="clear:both"></div>


===Ribonuclease A by Classical hanging drop method before high X-Ray dose on ESRF ID14-2 beamline===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
==About this Structure==
<references/>
3I6F is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6F OCA].
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Pancreatic ribonuclease]]
[[Category: Large Structures]]
[[Category: McSweeney, S.]]
[[Category: McSweeney S]]
[[Category: Nicolini, C.]]
[[Category: Nicolini C]]
[[Category: Pechkova, E.]]
[[Category: Pechkova E]]
[[Category: Ravelli, R.]]
[[Category: Ravelli R]]
[[Category: Tripathi, S K.]]
[[Category: Tripathi SK]]
[[Category: Disulfide bond]]
[[Category: Endonuclease]]
[[Category: Glycation]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Nuclease]]
[[Category: Ribonuclease some]]
[[Category: Secreted]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  7 08:39:39 2010''

Latest revision as of 04:55, 21 November 2024

Ribonuclease A by Classical hanging drop method before high X-Ray dose on ESRF ID14-2 beamlineRibonuclease A by Classical hanging drop method before high X-Ray dose on ESRF ID14-2 beamline

Structural highlights

3i6f is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNAS1_BOVIN Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

3i6f, resolution 1.30Å

Drag the structure with the mouse to rotate

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