3gci: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:3gci.jpg|left|200px]]
-<!--
+==Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal Amyloid Beta Heptapeptide at 2 A Resolution==
-The line below this paragraph, containing "STRUCTURE_3gci", creates the "Structure Box" on the page.
+<StructureSection load='3gci' size='340' side='right'caption='[[3gci]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3gci]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GCI FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-{{STRUCTURE_3gci|  PDB=3gci  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gci OCA], [https://pdbe.org/3gci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gci RCSB], [https://www.ebi.ac.uk/pdbsum/3gci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gci ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PA2A3_NAJSG PA2A3_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gci_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gci ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal Amyloid Beta Heptapeptide at 2 A Resolution===
+==See Also==
+*[[Amyloid precursor protein 3D structures|Amyloid precursor protein 3D structures]]
+*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
-==About this Structure==
+__TOC__
-GCI is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCI OCA].
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
 [[Category: Naja sagittifera]]
-[[Category: Bhushan, A.]]
+[[Category: Bhushan A]]
-[[Category: Kaur, P.]]
+[[Category: Kaur P]]
-[[Category: Mirza, Z.]]
+[[Category: Mirza Z]]
-[[Category: Sharma, S.]]
+[[Category: Sharma S]]
-[[Category: Singh, N.]]
+[[Category: Singh N]]
-[[Category: Singh, T P.]]
+[[Category: Singh TP]]
-[[Category: Sinha, M.]]
+[[Category: Sinha M]]
-[[Category: Srinivasan, A.]]
+[[Category: Srinivasan A]]
-[[Category: Vikram, G.]]
+[[Category: Vikram G]]
-[[Category: Amyloid beta]]
-[[Category: Calcium]]
-[[Category: Crystal structure]]
-[[Category: Heptapeptide]]
-[[Category: Hydrolase]]
-[[Category: Lipid degradation]]
-[[Category: Metal-binding]]
-[[Category: Phospholipase a2]]
-[[Category: Secreted]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 11 11:29:06 2009''