3fpx: Difference between revisions

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-{{Seed}}
-[[Image:3fpx.jpg|left|200px]]
-<!--
+==Native fungus laccase from Trametes hirsuta==
-The line below this paragraph, containing "STRUCTURE_3fpx", creates the "Structure Box" on the page.
+<StructureSection load='3fpx' size='340' side='right'caption='[[3fpx]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3fpx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trametes_hirsuta Trametes hirsuta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FPX FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-{{STRUCTURE_3fpx|  PDB=3fpx  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fpx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fpx OCA], [https://pdbe.org/3fpx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fpx RCSB], [https://www.ebi.ac.uk/pdbsum/3fpx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fpx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/B2L9C1_TRAHI B2L9C1_TRAHI]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/3fpx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fpx ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Laccase from the fungus Coriolus hirsutus has been purified. Crystals of the enzyme suitable for X-ray structure analysis have been obtained under optimized crystallization conditions using polyethylene glycol as a precipitant. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 50.65, b = 74.01, c = 124.83 A, and contain 40% solvent and a single molecule of laccase in the asymmetric unit. X-ray data were collected to 1.85 A at the copper edge and the four copper sites have been located from the anomalous signal. The obtained SAD phases with subsequent density modification produced a promising initial electron-density map.
-===Native fungus laccase from Trametes hirsuta===
+Crystallization and preliminary X-ray analysis of a four-copper laccase from Coriolus hirsutus.,Pegasova TV, Zwart P, Koroleva OV, Stepanova EV, Rebrikov DV, Lamzin VS Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1459-61. Epub 2003, Jul 23. PMID:012876350<ref>PMID:012876350</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 3fpx" style="background-color:#fffaf0;"></div>
-==About this Structure==
+==See Also==
-FPX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Trametes_hirsuta Trametes hirsuta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPX OCA].
+*[[Laccase 3D structures|Laccase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:12876350</ref><references group="xtra"/>
+__TOC__
-[[Category: Laccase]]
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Trametes hirsuta]]
-[[Category: Cherkashin, E A.]]
+[[Category: Cherkashin EA]]
-[[Category: Fedorova, T V.]]
+[[Category: Fedorova TV]]
-[[Category: Koroleva, O V.]]
+[[Category: Koroleva OV]]
-[[Category: Kurzeev, S A.]]
+[[Category: Kurzeev SA]]
-[[Category: Lamzin, V S.]]
+[[Category: Lamzin VS]]
-[[Category: Polyakov, K M.]]
+[[Category: Polyakov KM]]
-[[Category: Stepanova, E V.]]
+[[Category: Stepanova EV]]
-[[Category: Strokopytov, B V.]]
+[[Category: Strokopytov BV]]
-[[Category: 4-copper protein]]
-[[Category: Beta sheet]]
-[[Category: Copper]]
-[[Category: Metal-binding]]
-[[Category: Oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:58:07 2009''