3fom: Difference between revisions

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==Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide IQQSIERL==
==Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide IQQSIERL==
<StructureSection load='3fom' size='340' side='right' caption='[[3fom]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3fom' size='340' side='right'caption='[[3fom]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fom]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FOM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FOM FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fom]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FOM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fol|3fol]], [[3fon|3fon]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">B2m ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fom OCA], [https://pdbe.org/3fom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fom RCSB], [https://www.ebi.ac.uk/pdbsum/3fom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fom ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fom OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fom RCSB], [http://www.ebi.ac.uk/pdbsum/3fom PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/3fom_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/3fom_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fom ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3fom" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[Phycocyanobilin:ferredoxin oxidoreductase|Phycocyanobilin:ferredoxin oxidoreductase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Brims, D R]]
[[Category: Brims DR]]
[[Category: DiLorenzo, T P]]
[[Category: DiLorenzo TP]]
[[Category: Hattori, M]]
[[Category: Hattori M]]
[[Category: Hunt, D F]]
[[Category: Hunt DF]]
[[Category: Jarchum, I]]
[[Category: Jarchum I]]
[[Category: Lund, T]]
[[Category: Lund T]]
[[Category: Malashkevich, V N]]
[[Category: Malashkevich VN]]
[[Category: Mikesh, L]]
[[Category: Mikesh L]]
[[Category: Nathenson, S G]]
[[Category: Nathenson SG]]
[[Category: Palmieri, E]]
[[Category: Palmieri E]]
[[Category: Qian, J]]
[[Category: Qian J]]
[[Category: Ramagopal, U A]]
[[Category: Ramagopal UA]]
[[Category: Shabanowitz, J]]
[[Category: Shabanowitz J]]
[[Category: Yamada, T]]
[[Category: Yamada T]]
[[Category: Class i mhc]]
[[Category: Diabetes-protective effect]]
[[Category: Immune response]]
[[Category: Immune system]]
[[Category: Immunoglobulin domain]]
[[Category: Mhc i]]
[[Category: Peptide complex]]
[[Category: Secreted]]

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