2zx6: Difference between revisions

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<StructureSection load='2zx6' size='340' side='right'caption='[[2zx6]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
<StructureSection load='2zx6' size='340' side='right'caption='[[2zx6]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zx6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZX6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zx6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZX6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZX6:2-(1H-INDOL-3-YL)-N-{[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYLPIPERIDIN-2-YL]METHYL}ACETAMIDE'>ZX6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hl8|1hl8]], [[2zwy|2zwy]], [[2zwz|2zwz]], [[2zx5|2zx5]], [[2zx7|2zx7]], [[2zx8|2zx8]], [[2zx9|2zx9]], [[2zxa|2zxa]], [[2zxb|2zxb]], [[2zxd|2zxd]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZX6:2-(1H-INDOL-3-YL)-N-{[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYLPIPERIDIN-2-YL]METHYL}ACETAMIDE'>ZX6</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-L-fucosidase Alpha-L-fucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.51 3.2.1.51] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zx6 OCA], [https://pdbe.org/2zx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zx6 RCSB], [https://www.ebi.ac.uk/pdbsum/2zx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zx6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zx6 OCA], [http://pdbe.org/2zx6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zx6 RCSB], [http://www.ebi.ac.uk/pdbsum/2zx6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zx6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9WYE2_THEMA Q9WYE2_THEMA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zx6_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zx6_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alpha-L-fucosidase]]
[[Category: Atcc 43589]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ho, C W]]
[[Category: Thermotoga maritima]]
[[Category: Ko, T P]]
[[Category: Ho C-W]]
[[Category: Lin, C H]]
[[Category: Ko T-P]]
[[Category: Wang, A H.J]]
[[Category: Lin C-H]]
[[Category: Wu, H J]]
[[Category: Wang AH-J]]
[[Category: Hydrolase]]
[[Category: Wu H-J]]
[[Category: Tim barrel]]

Latest revision as of 04:34, 21 November 2024

alpha-L-fucosidase complexed with inhibitor, F10-1Calpha-L-fucosidase complexed with inhibitor, F10-1C

Structural highlights

2zx6 is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.42Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9WYE2_THEMA

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2zx6, resolution 2.42Å

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OCA