3exc: Difference between revisions

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-{{Seed}}
-[[Image:3exc.jpg|left|200px]]
-<!--
+==Structure of the RNA'se SSO8090 from Sulfolobus solfataricus==
-The line below this paragraph, containing "STRUCTURE_3exc", creates the "Structure Box" on the page.
+<StructureSection load='3exc' size='340' side='right'caption='[[3exc]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3exc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-{{STRUCTURE_3exc|  PDB=3exc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exc OCA], [https://pdbe.org/3exc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exc RCSB], [https://www.ebi.ac.uk/pdbsum/3exc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exc ProSAT], [https://www.topsan.org/Proteins/MCSG/3exc TOPSAN]</span></td></tr>
+</table>
-===Structure of the RNA'se SSO8090 from Sulfolobus solfataricus===
+== Function ==
+[https://www.uniprot.org/uniprot/CAS2B_SACS2 CAS2B_SACS2] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).<ref>PMID:18482976</ref>
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-EXC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXC OCA].
+Check<jmol>
-[[Category: Sulfolobus solfataricus]]
+  <jmolCheckbox>
-[[Category: Joachimiak, A.]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3exc_consurf.spt"</scriptWhenChecked>
-[[Category: Kagan, O.]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
-[[Category: Onopriyenko, O.]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Savchenko, A.]]
+  </jmolCheckbox>
-[[Category: Singer, A U.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3exc ConSurf].
-[[Category: Skarina, T.]]
+<div style="clear:both"></div>
-[[Category: Tan, K.]]
+== References ==
-[[Category: Yakunin, A F.]]
+<references/>
-[[Category: Catalytic aspartate]]
+__TOC__
-[[Category: Dimer]]
+</StructureSection>
-[[Category: Double split beta-alpha-beta fold]]
+[[Category: Large Structures]]
-[[Category: Ferredoxin fold]]
+[[Category: Saccharolobus solfataricus]]
-[[Category: Hydrolase]]
+[[Category: Edwards AM]]
-[[Category: Rna'ase]]
+[[Category: Joachimiak A]]
+[[Category: Kagan O]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 12 10:51:18 2008''
+[[Category: Onopriyenko O]]
+[[Category: Savchenko A]]
+[[Category: Singer AU]]
+[[Category: Skarina T]]
+[[Category: Tan K]]
+[[Category: Yakunin AF]]