3elb: Difference between revisions

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-[[Image:3elb.png|left|200px]]
-{{STRUCTURE_3elb|  PDB=3elb  |  SCENE=  }}
+==Human CTP: Phosphoethanolamine Cytidylyltransferase in complex with CMP==
+<StructureSection load='3elb' size='340' side='right'caption='[[3elb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===Human CTP: Phosphoethanolamine Cytidylyltransferase in complex with CMP===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3elb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ELB FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-[[3elb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELB OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3elb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3elb OCA], [https://pdbe.org/3elb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3elb RCSB], [https://www.ebi.ac.uk/pdbsum/3elb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3elb ProSAT]</span></td></tr>
-[[Category: Ethanolamine-phosphate cytidylyltransferase]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PCY2_HUMAN PCY2_HUMAN] Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/3elb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3elb ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Andersson, J.]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Andersson J]]
-[[Category: Berg, S Van Den.]]
+[[Category: Arrowsmith CH]]
-[[Category: Berglund, H.]]
+[[Category: Berglund H]]
-[[Category: Bountra, C.]]
+[[Category: Bountra C]]
-[[Category: Collins, R.]]
+[[Category: Collins R]]
-[[Category: Dahlgren, L G.]]
+[[Category: Dahlgren LG]]
-[[Category: Edwards, A M.]]
+[[Category: Edwards AM]]
-[[Category: Flodin, S.]]
+[[Category: Flodin S]]
-[[Category: Flores, A.]]
+[[Category: Flores A]]
-[[Category: Graslund, S.]]
+[[Category: Graslund S]]
-[[Category: Hammarstrom, M.]]
+[[Category: Hammarstrom M]]
-[[Category: Johansson, A.]]
+[[Category: Johansson A]]
-[[Category: Johansson, I.]]
+[[Category: Johansson I]]
-[[Category: Karlberg, T.]]
+[[Category: Karlberg T]]
-[[Category: Kotenyova, T.]]
+[[Category: Kotenyova T]]
-[[Category: Lehtio, L.]]
+[[Category: Lehtio L]]
-[[Category: Moche, M.]]
+[[Category: Moche M]]
-[[Category: Nilsson, M E.]]
+[[Category: Nilsson ME]]
-[[Category: Nordlund, P.]]
+[[Category: Nordlund P]]
-[[Category: Nyman, T.]]
+[[Category: Nyman T]]
-[[Category: Persson, C.]]
+[[Category: Persson C]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Sagemark J]]
-[[Category: Sagemark, J.]]
+[[Category: Schuler H]]
-[[Category: Schuler, H.]]
+[[Category: Thorsell AG]]
-[[Category: Thorsell, A G.]]
+[[Category: Tresaugues L]]
-[[Category: Tresaugues, L.]]
+[[Category: Van Den Berg S]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt J]]
-[[Category: Welin, M.]]
+[[Category: Welin M]]
-[[Category: Wikstrom, M.]]
+[[Category: Wikstrom M]]
-[[Category: Wisniewska, M.]]
+[[Category: Wisniewska M]]
-[[Category: Cmp]]
-[[Category: Ctp]]
-[[Category: Cytidylyltransferase]]
-[[Category: Kennedy pathway]]
-[[Category: Nucleotidyltransferase]]
-[[Category: Phosphoethanolamine]]
-[[Category: Phospholipid biosynthesis]]
-[[Category: Sgc]]
-[[Category: Structural genomics consortium]]
-[[Category: Transferase]]