3dih: Difference between revisions

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-{{Seed}}
-[[Image:3dih.png|left|200px]]
-<!--
+==Crystal structure of ammodytin L==
-The line below this paragraph, containing "STRUCTURE_3dih", creates the "Structure Box" on the page.
+<StructureSection load='3dih' size='340' side='right'caption='[[3dih]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3dih]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vipera_ammodytes_ammodytes Vipera ammodytes ammodytes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DIH FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dih OCA], [https://pdbe.org/3dih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dih RCSB], [https://www.ebi.ac.uk/pdbsum/3dih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dih ProSAT]</span></td></tr>
-{{STRUCTURE_3dih|  PDB=3dih  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PA2HL_VIPAA PA2HL_VIPAA] Snake venom phospholipase A2 homolog that is very active in inducing myonecrosis in vivo and shows a potent calcium-independent membrane-damaging activity in vitro, most probably by binding and incorporating in the membrane. Also acts as a presynaptic neurotoxin.<ref>PMID:10653156</ref> <ref>PMID:11005629</ref> <ref>PMID:1765075</ref> <ref>PMID:17927217</ref> <ref>PMID:7662700</ref> <ref>PMID:8835336</ref> <ref>PMID:8973554</ref> <ref>PMID:9514950</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/di/3dih_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dih ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of ammodytin L===
+==See Also==
+*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
+*[[Phospholipase A2 homolog|Phospholipase A2 homolog]]
-==About this Structure==
+== References ==
-DIH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Vipera_ammodytes_ammodytes Vipera ammodytes ammodytes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DIH OCA].
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Vipera ammodytes ammodytes]]
-[[Category: Guncar, G.]]
+[[Category: Guncar G]]
-[[Category: Krizaj, I.]]
+[[Category: Krizaj I]]
-[[Category: Turk, D.]]
+[[Category: Turk D]]
-[[Category: Myotoxin]]
-[[Category: Phospholipase a2 fold]]
-[[Category: Secreted]]
-[[Category: Toxin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:38:51 2009''