5qkf: Difference between revisions
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<StructureSection load='5qkf' size='340' side='right'caption='[[5qkf]], [[Resolution|resolution]] 2.14Å' scene=''> | <StructureSection load='5qkf' size='340' side='right'caption='[[5qkf]], [[Resolution|resolution]] 2.14Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5qkf]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5qkf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QKF FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.141Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qkf OCA], [https://pdbe.org/5qkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qkf RCSB], [https://www.ebi.ac.uk/pdbsum/5qkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qkf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DSBA_ECOLI DSBA_ECOLI] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.<ref>PMID:1429594</ref> <ref>PMID:22267510</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bentley | [[Category: Bentley MR]] | ||
[[Category: Doak | [[Category: Doak BC]] | ||
[[Category: Ilyichova | [[Category: Ilyichova OV]] | ||
[[Category: Scanlon | [[Category: Scanlon MJ]] | ||