2pt5: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5==
==Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5==
<StructureSection load='2pt5' size='340' side='right' caption='[[2pt5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2pt5' size='340' side='right'caption='[[2pt5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pt5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PT5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pt5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PT5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pt5 OCA], [https://pdbe.org/2pt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2pt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pt5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2pt5 TOPSAN]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Shikimate_kinase Shikimate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.71 2.7.1.71] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pt5 OCA], [http://pdbe.org/2pt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pt5 RCSB], [http://www.ebi.ac.uk/pdbsum/2pt5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pt5 ProSAT], [http://www.topsan.org/Proteins/RSGI/2pt5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AROK_AQUAE AROK_AQUAE]] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity).  
[https://www.uniprot.org/uniprot/AROK_AQUAE AROK_AQUAE] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 17: Line 15:
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pt/2pt5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pt/2pt5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
Line 24: Line 22:


==See Also==
==See Also==
*[[Shikimate kinase|Shikimate kinase]]
*[[Shikimate kinase 3D structures|Shikimate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aquae]]
[[Category: Aquifex aeolicus VF5]]
[[Category: Shikimate kinase]]
[[Category: Large Structures]]
[[Category: Ebihara, A]]
[[Category: Ebihara A]]
[[Category: Jeyakanthan, J]]
[[Category: Jeyakanthan J]]
[[Category: Kuramitsu, S]]
[[Category: Kuramitsu S]]
[[Category: Nithya, N]]
[[Category: Nithya N]]
[[Category: Structural genomic]]
[[Category: Shimada A]]
[[Category: Shimada, A]]
[[Category: Shinkai A]]
[[Category: Shinkai, A]]
[[Category: Shiro Y]]
[[Category: Shiro, Y]]
[[Category: Velmurugan D]]
[[Category: Velmurugan, D]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Amino-acid biosynthesis]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nucleotide-binding]]
[[Category: P-loop kinase]]
[[Category: Rsgi]]
[[Category: Shikimate pathway]]
[[Category: Transferase]]

Latest revision as of 11:30, 30 October 2024

Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5

Structural highlights

2pt5 is a 4 chain structure with sequence from Aquifex aeolicus VF5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

AROK_AQUAE Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pt5, resolution 2.10Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2pt5&oldid=4205204"