2eq9: Difference between revisions

New page: left|200px {{Structure |PDB= 2eq9 |SIZE=350|CAPTION= <scene name='initialview01'>2eq9</scene>, resolution 2.09Å |SITE= <scene name='pdbsite=AC1:Fad+Binding+Site+...
 
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[[Image:2eq9.jpg|left|200px]]


{{Structure
==Crystal structure of lipoamide dehydrogenase from thermus thermophilus HB8 with psbdb==
|PDB= 2eq9 |SIZE=350|CAPTION= <scene name='initialview01'>2eq9</scene>, resolution 2.09&Aring;
<StructureSection load='2eq9' size='340' side='right'caption='[[2eq9]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Fad+Binding+Site+For+Residue+A+8482'>AC1</scene>, <scene name='pdbsite=AC2:Fad+Binding+Site+For+Residue+B+1482'>AC2</scene>, <scene name='pdbsite=AC3:Fad+Binding+Site+For+Residue+D+2482'>AC3</scene>, <scene name='pdbsite=AC4:Fad+Binding+Site+For+Residue+E+3482'>AC4</scene>, <scene name='pdbsite=AC5:Fad+Binding+Site+For+Residue+G+4482'>AC5</scene>, <scene name='pdbsite=AC6:Fad+Binding+Site+For+Residue+H+5482'>AC6</scene>, <scene name='pdbsite=AC7:Fad+Binding+Site+For+Residue+J+6482'>AC7</scene> and <scene name='pdbsite=AC8:Fad+Binding+Site+For+Residue+K+7482'>AC8</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>
<table><tr><td colspan='2'>[[2eq9]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQ9 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrolipoyl_dehydrogenase Dihydrolipoyl dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.4 1.8.1.4] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
|GENE= TTHA0233 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus]), TTHA0232 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK06416 PRK06416], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02852 Pyr_redox_dim], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00070 Pyr_redox], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02817 E3_binding]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eq9 OCA], [https://pdbe.org/2eq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2eq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eq9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eq9 TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eq9 OCA], [http://www.ebi.ac.uk/pdbsum/2eq9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eq9 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/Q5SLR0_THET8 Q5SLR0_THET8]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/2eq9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eq9 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of lipoamide dehydrogenase from thermus thermophilus HB8 with psbdb'''
==See Also==
 
*[[Dihydrolipoamide acetyltransferase 3D structures|Dihydrolipoamide acetyltransferase 3D structures]]
 
*[[Dihydrolipoamide dehydrogenase|Dihydrolipoamide dehydrogenase]]
==About this Structure==
__TOC__
2EQ9 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQ9 OCA].
</StructureSection>
[[Category: Dihydrolipoyl dehydrogenase]]
[[Category: Large Structures]]
[[Category: Protein complex]]
[[Category: Thermus thermophilus HB8]]
[[Category: Thermus thermophilus]]
[[Category: Kamiya N]]
[[Category: Kamiya, N.]]
[[Category: Nakai T]]
[[Category: Nakai, T.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: oxidoreductase]]
[[Category: protein-protein complex]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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