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[[Image:2omk.gif|left|200px]]


{{Structure
==Structure of the Bacteroides Thetaiotaomicron Thiamin Pyrophosphokinase==
|PDB= 2omk |SIZE=350|CAPTION= <scene name='initialview01'>2omk</scene>, resolution 1.80&Aring;
<StructureSection load='2omk' size='340' side='right'caption='[[2omk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=SNN:L-3-AMINOSUCCINIMIDE'>SNN</scene>
<table><tr><td colspan='2'>[[2omk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OMK FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine_diphosphokinase Thiamine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.2 2.7.6.2] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= BT2397 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=818 Bacteroides thetaiotaomicron])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SNN:L-3-AMINOSUCCINIMIDE'>SNN</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1564 THI80], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam04263 TPK_catalytic]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2omk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2omk OCA], [https://pdbe.org/2omk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2omk RCSB], [https://www.ebi.ac.uk/pdbsum/2omk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2omk ProSAT], [https://www.topsan.org/Proteins/MCSG/2omk TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2omk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2omk OCA], [http://www.ebi.ac.uk/pdbsum/2omk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2omk RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/Q8A545_BACTN Q8A545_BACTN]
 
== Evolutionary Conservation ==
'''Structure of the Bacteroides Thetaiotaomicron Thiamin Pyrophosphokinase'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/2omk_consurf.spt"</scriptWhenChecked>
2OMK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OMK OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Bacteroides thetaiotaomicron]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Thiamine diphosphokinase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2omk ConSurf].
[[Category: Abdullah, J.]]
<div style="clear:both"></div>
[[Category: Anderson, W F.]]
__TOC__
[[Category: Collart, F R.]]
</StructureSection>
[[Category: Joachimiak, A.]]
[[Category: Bacteroides thetaiotaomicron VPI-5482]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Large Structures]]
[[Category: Minasov, G.]]
[[Category: Abdullah J]]
[[Category: Shuvalova, L.]]
[[Category: Anderson WF]]
[[Category: Vorontsov, I I.]]
[[Category: Collart FR]]
[[Category: crystal structure]]
[[Category: Joachimiak A]]
[[Category: mcsg]]
[[Category: Minasov G]]
[[Category: midwest center for structural genomic]]
[[Category: Shuvalova L]]
[[Category: protein structure initiative]]
[[Category: Vorontsov II]]
[[Category: psi-2]]
[[Category: structural genomic]]
[[Category: succinimide]]
[[Category: thiamin pyrophosphokinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:19:59 2008''

Latest revision as of 11:24, 30 October 2024

Structure of the Bacteroides Thetaiotaomicron Thiamin PyrophosphokinaseStructure of the Bacteroides Thetaiotaomicron Thiamin Pyrophosphokinase

Structural highlights

2omk is a 2 chain structure with sequence from Bacteroides thetaiotaomicron VPI-5482. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q8A545_BACTN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2omk, resolution 1.80Å

Drag the structure with the mouse to rotate

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OCA
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