2gfi: Difference between revisions

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-{{Seed}}
-[[Image:2gfi.png|left|200px]]
-<!--
+==Crystal structure of the phytase from D. castellii at 2.3 A==
-The line below this paragraph, containing "STRUCTURE_2gfi", creates the "Structure Box" on the page.
+<StructureSection load='2gfi' size='340' side='right'caption='[[2gfi]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2gfi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Debaryomyces_castellii Debaryomyces castellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GFI FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-{{STRUCTURE_2gfi|  PDB=2gfi  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gfi OCA], [https://pdbe.org/2gfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gfi RCSB], [https://www.ebi.ac.uk/pdbsum/2gfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gfi ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A2TBB4_9ASCO A2TBB4_9ASCO]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gfi_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gfi ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Phytate (myo-inositol hexakisphosphate) is the primary storage form of phosphate in seeds and legumes (Reddy et al., 1982). Phytases are phosphatases that hydrolyze phytate to less phosphorylated myo-inositol derivatives and inorganic phosphate. The crystal structure of phytase from Debaryomyces castellii has been determined at 2.3 A resolution. The crystals belonged to space group P6(5)22, with unit-cell parameters a = 121.65, c = 332.24 A. The structure was solved by molecular replacement and refined to a final R factor of 15.7% (R(free) = 20.9%). The final model consists of a dimer (with two monomers of 458 residues), five NAG molecules and 628 water molecules.
-===Crystal structure of the phytase from D. castellii at 2.3 A===
+Structure of Debaryomyces castellii CBS 2923 phytase.,Ragon M, Hoh F, Aumelas A, Chiche L, Moulin G, Boze H Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr 1;65(Pt, 4):321-6. Epub 2009 Mar 25. PMID:19342770<ref>PMID:19342770</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 2gfi" style="background-color:#fffaf0;"></div>
-<!--
+==See Also==
-The line below this paragraph, {{ABSTRACT_PUBMED_19342770}}, adds the Publication Abstract to the page
+*[[Phytase 3D structures|Phytase 3D structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 19342770 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_19342770}}
+__TOC__
+</StructureSection>
-==About this Structure==
-GFI is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Debaryomyces_castellii Debaryomyces castellii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GFI OCA].
-==Reference==
-<ref group="xtra">PMID:19342770</ref><references group="xtra"/>
-[[Category: 3-phytase]]
 [[Category: Debaryomyces castellii]]
-[[Category: Hoh, F.]]
+[[Category: Large Structures]]
-[[Category: Hydrolase]]
+[[Category: Hoh F]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 29 21:09:14 2009''