2c7b: Difference between revisions

No edit summary
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
==THE CRYSTAL STRUCTURE OF ESTE1, A NEW THERMOPHILIC AND THERMOSTABLE CARBOXYLESTERASE CLONED FROM A METAGENOMIC LIBRARY==
 
<StructureSection load='2c7b' size='340' side='right' caption='[[2c7b]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
==The Crystal Structure of EstE1, a New Thermophilic and Thermostable Carboxylesterase Cloned from a Metagenomic Library==
<StructureSection load='2c7b' size='340' side='right'caption='[[2c7b]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2c7b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Uncultured_archaea_archaeon Uncultured archaea archaeon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C7B FirstGlance]. <br>
<table><tr><td colspan='2'>[[2c7b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_archaeon Uncultured archaeon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7B FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bzq|2bzq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7b OCA], [https://pdbe.org/2c7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7b RCSB], [https://www.ebi.ac.uk/pdbsum/2c7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7b OCA], [http://pdbe.org/2c7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c7b RCSB], [http://www.ebi.ac.uk/pdbsum/2c7b PDBsum]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
Line 12: Line 12:
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7b_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7b_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c7b ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 29: Line 29:


==See Also==
==See Also==
*[[Carboxylesterase|Carboxylesterase]]
*[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carboxylesterase]]
[[Category: Large Structures]]
[[Category: Uncultured archaea archaeon]]
[[Category: Uncultured archaeon]]
[[Category: Byun, J S]]
[[Category: Byun J-S]]
[[Category: Cho, H S]]
[[Category: Cho H-S]]
[[Category: Kim, D U]]
[[Category: Kim D-U]]
[[Category: Oh, J W]]
[[Category: Oh J-W]]
[[Category: Rhee, J K]]
[[Category: Rhee J-K]]
[[Category: Alpha/beta hydrolase fold]]
[[Category: Carboxyesterase]]
[[Category: Hsl]]
[[Category: Hydrolase]]
[[Category: Thermophilic enzyme]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA