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==The crystal structure of DUF198 from Nitrosomonas europaea ATCC 19718==
==The crystal structure of DUF198 from Nitrosomonas europaea ATCC 19718==
<StructureSection load='2r5r' size='340' side='right' caption='[[2r5r]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
<StructureSection load='2r5r' size='340' side='right'caption='[[2r5r]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2r5r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea_atcc_19718 Nitrosomonas europaea atcc 19718]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R5R FirstGlance]. <br>
<table><tr><td colspan='2'>[[2r5r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nitrosomonas_europaea_ATCC_19718 Nitrosomonas europaea ATCC 19718]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NE1163 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=228410 Nitrosomonas europaea ATCC 19718])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5r OCA], [https://pdbe.org/2r5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5r RCSB], [https://www.ebi.ac.uk/pdbsum/2r5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5r ProSAT], [https://www.topsan.org/Proteins/MCSG/2r5r TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r5r RCSB], [http://www.ebi.ac.uk/pdbsum/2r5r PDBsum], [http://www.topsan.org/Proteins/MCSG/2r5r TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Y1163_NITEU Y1163_NITEU]] Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity).  
[https://www.uniprot.org/uniprot/GCH4_NITEU GCH4_NITEU] Converts GTP to 7,8-dihydroneopterin triphosphate.[HAMAP-Rule:MF_01527]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5r_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5r_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r5r ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Nitrosomonas europaea atcc 19718]]
[[Category: Large Structures]]
[[Category: Bargassa, M]]
[[Category: Nitrosomonas europaea ATCC 19718]]
[[Category: Bigelow, L]]
[[Category: Bargassa M]]
[[Category: Freeman, L]]
[[Category: Bigelow L]]
[[Category: Joachimiak, A]]
[[Category: Freeman L]]
[[Category: Structural genomic]]
[[Category: Joachimiak A]]
[[Category: Nocek, B]]
[[Category: Nocek B]]
[[Category: Patterson, S]]
[[Category: Patterson S]]
[[Category: Tan, K]]
[[Category: Tan K]]
[[Category: Wu, R]]
[[Category: Wu R]]
[[Category: Apc86493]]
[[Category: Duf198]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

Latest revision as of 12:29, 6 November 2024

The crystal structure of DUF198 from Nitrosomonas europaea ATCC 19718The crystal structure of DUF198 from Nitrosomonas europaea ATCC 19718

Structural highlights

2r5r is a 1 chain structure with sequence from Nitrosomonas europaea ATCC 19718. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.05Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

GCH4_NITEU Converts GTP to 7,8-dihydroneopterin triphosphate.[HAMAP-Rule:MF_01527]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2r5r, resolution 3.05Å

Drag the structure with the mouse to rotate

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OCA