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==NMR structure of DEF-BAT, a mutant of anopheles defensin DEF-AAA==
==NMR structure of DEF-BAT, a mutant of anopheles defensin DEF-AAA==
<StructureSection load='2e3f' size='340' side='right' caption='[[2e3f]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2e3f' size='340' side='right'caption='[[2e3f]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2e3f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E3F FirstGlance]. <br>
<table><tr><td colspan='2'>[[2e3f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E3F FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ny8|2ny8]], [[2ny9|2ny9]], [[2nz3|2nz3]], [[2e3e|2e3e]], [[2e3g|2e3g]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7165 Anopheles gambiae])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3f OCA], [https://pdbe.org/2e3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e3f RCSB], [https://www.ebi.ac.uk/pdbsum/2e3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e3f ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e3f RCSB], [http://www.ebi.ac.uk/pdbsum/2e3f PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/DEFI_ANOGA DEFI_ANOGA] Responsible for the anti Gram-positive activity of immune hemolymph (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3f_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3f_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e3f ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2e3f" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Defensin|Defensin]]
*[[Defensin 3D structures|Defensin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Anopheles gambiae]]
[[Category: Anopheles gambiae]]
[[Category: Barbault, F.]]
[[Category: Large Structures]]
[[Category: Landon, C.]]
[[Category: Barbault F]]
[[Category: Vovelle, F.]]
[[Category: Landon C]]
[[Category: Antibacterial]]
[[Category: Vovelle F]]
[[Category: Antimicrobial protein]]
[[Category: Csab motif]]
[[Category: Insect defensin]]

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