2ef5: Difference between revisions

New page: left|200px<br /><applet load="2ef5" size="350" color="white" frame="true" align="right" spinBox="true" caption="2ef5, resolution 2.00Å" /> '''Crystal structure of...
 
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[[Image:2ef5.gif|left|200px]]<br /><applet load="2ef5" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ef5, resolution 2.00&Aring;" />
'''Crystal structure of the arginase from thermus thermophilus'''<br />


==About this Structure==
==Crystal structure of the arginase from thermus thermophilus==
2EF5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=GAI:'>GAI</scene> and <scene name='pdbligand=LYS:'>LYS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EF5 OCA].  
<StructureSection load='2ef5' size='340' side='right'caption='[[2ef5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Arginase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2ef5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EF5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ef5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ef5 OCA], [https://pdbe.org/2ef5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ef5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ef5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ef5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ef5 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5SI78_THET8 Q5SI78_THET8]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/2ef5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ef5 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Arginase 3D structures|Arginase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Karthe, P.]]
[[Category: Karthe P]]
[[Category: Kumarevel, T.S.]]
[[Category: Kumarevel TS]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu S]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: GAI]]
[[Category: LYS]]
[[Category: MN]]
[[Category: arginase]]
[[Category: hydrolase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: thermus thermophilus]]
[[Category: ttha1496]]
 
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