3bi5: Difference between revisions

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-[[Image:3bi5.jpg|left|200px]]
- {{Structure
+==Crystal structures of fms1 in complex with its inhibitors==
-|PDB= 3bi5 |SIZE=350|CAPTION= <scene name='initialview01'>3bi5</scene>, resolution 2.500&Aring;
+<StructureSection load='3bi5' size='340' side='right'caption='[[3bi5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=DIA:OCTANE 1,8-DIAMINE'>DIA</scene>
+<table><tr><td colspan='2'>[[3bi5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BI5 FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Polyamine_oxidase Polyamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.11 1.5.3.11]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-|GENE= Fms1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIA:OCTANE+1,8-DIAMINE'>DIA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bi5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bi5 OCA], [https://pdbe.org/3bi5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bi5 RCSB], [https://www.ebi.ac.uk/pdbsum/3bi5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bi5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FMS1_YEAST FMS1_YEAST] Involved in the production of beta-alanine, a precursor of pantothenic acid. Multicopy suppressor of fenpropimorph resistance.<ref>PMID:12670477</ref> <ref>PMID:14617780</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/3bi5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bi5 ConSurf].
+<div style="clear:both"></div>
-'''Crystal structures of fms1 in complex with its inhibitors'''
+==See Also==
+*[[Polyamine oxidase|Polyamine oxidase]]
+== References ==
-==About this Structure==
+<references/>
-BI5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BI5 OCA].
+__TOC__
-[[Category: Polyamine oxidase]]
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Single protein]]
+[[Category: Hao Q]]
-[[Category: Hao, Q.]]
+[[Category: Huang Q]]
-[[Category: Huang, Q.]]
-[[Category: DIA]]
-[[Category: FAD]]
-[[Category: enzyme-inhibitor complex]]
-[[Category: oxidoreductase]]
-[[Category: polyamine oxidase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:59:05 2008''